Vitamin C untuk Upper Respiratory Tract Infections
B Bukti Setidaknya satu uji coba acak mendukung hal ini, dengan hasil yang sebagian besar konsisten.Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.
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B
Kesimpulan
Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.
Key Study Findings
Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: Elite/professional cyclists nutrition review
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
Efek: None
None
Populasi: Children with inflammatory bowel disease (review)
Other
Circulating micronutrient levels and respiratory infection susceptibility and severity: a bidirectional Mendelian randomization analysis.
Dose: 12 circulating micronutrients
vs: Genetic instrument comparison
Outcome: URTI, LRTI, pneumonia risk
Efek: None
None
Populasi: Large genetic cohort (MR analysis)
Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals
vs: None
Outcome: Immune response modulation in COVID-19
Efek: None
None
Populasi: COVID-19 patients with gut dysbiosis
Randomized Controlled Trial
Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some …
Dose: None
vs: Basal diet without supplementation
Outcome: Antioxidant status, hematology, growth in broilers
Efek: None
None
Populasi: Broiler chickens
Randomized Controlled Trial
n=171
24 weeks
Double-blind
Probiotics with vitamin C for the prevention of upper respiratory tract symptoms in children aged …
Dose: 12.5 billion cfu/d
vs: placebo
Outcome: None
Efek: or 6
P=0.0300
Populasi: None
Key Statistics
30
Studi
10000
Peserta
↑
Positive
B
Peringkat
Referenced Papers
Nutrients
2025
4 sitasi
International journal of …
2025
2 sitasi
Journal of translational …
2024
2 sitasi
Frontiers in nutrition
2024
1 sitasi
Biological trace element …
2022
5 sitasi
Beneficial microbes
2021
18 sitasi
European journal of …
2021
Nutrients
2020
75 sitasi
Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A meta-analysis in children.
Meta-Analysis
European journal of …
2019
54 sitasi
Journal of evidence-based …
2017
134 sitasi
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2017
18 sitasi
Zhongguo Zhong yao …
2017
European journal of …
2015
70 sitasi
World journal of …
2015
62 sitasi
Zhongguo Zhong yao …
2014
4 sitasi
Zhongguo Zhong yao …
2013
European journal of …
2012
225 sitasi
The British journal …
2012
40 sitasi
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2012
Journal of the …
2011
8 sitasi
International journal of …
2008
11 sitasi
American journal of …
2006
51 sitasi
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2003
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2003
The British journal …
2002
358 sitasi
Primary care
2002
56 sitasi
American family physician
2002
Canadian journal of …
2001
72 sitasi
Medicine and science …
2000
262 sitasi
Medicine and science …
2000
248 sitasi
Alternative medicine review …
2000
Canadian journal of …
1998
41 sitasi
Journal of applied …
1997
434 sitasi
International journal of …
1997
167 sitasi
Exercise immunology review
1997
27 sitasi
Respiration; international review …
1989
25 sitasi
Scandinavian journal of …
1977
56 sitasi
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 75-90 mg/day
- acuteillness:
- 1,000-2,000 mg/day
- immunesupport:
- 200-1,000 mg/day
Batas atas: 2,000 mg/day
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| 12 circulating micronutrients | -- | Mixed | -- |
| Probiotics, nutraceuticals | -- | Positive | -- |
| None | -- | Positive | -- |
| 12.5 billion cfu/d | 24 weeks | Mixed | 171 |
| 45% | 988 weeks | Positive | 26282 |
| None | 13.0 weeks | Mixed | 3135 |
Waktu terbaik diminum: With meals; divide doses >500 mg for better absorption
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Gastrointestinal distress (nausea, diarrhea, cramps) at high doses
- ⚠ Increased risk of kidney stones in susceptible individuals
- ⚠ Interference with certain lab tests (glucose, occult blood)
- ⚠ Iron overload risk in hemochromatosis patients
Interaksi yang Diketahui
- ● Enhances non-heme iron absorption (beneficial or harmful depending on iron status)
- ● High doses may reduce effectiveness of certain chemotherapy agents
- ● May interfere with anticoagulant therapy (warfarin) at high doses
- ● Aluminum-containing antacids (increased aluminum absorption)
Asupan atas yang dapat ditoleransi: 2,000 mg/day
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Vitamin C help with Upper Respiratory Tract Infections?
Based on 30 studies with 10,000 participants, there is moderate evidence from clinical studies that Vitamin C may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).
How much Vitamin C should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 75-90 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin C?
Reported side effects may include Gastrointestinal distress (nausea, diarrhea, cramps) at high doses, Increased risk of kidney stones in susceptible individuals, Interference with certain lab tests (glucose, occult blood), Iron overload risk in hemochromatosis patients. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin C and Upper Respiratory Tract Infections?
We rate the evidence as Grade B (Good Evidence). This rating is based on 30 peer-reviewed studies with 10,000 total participants. The overall direction of effect is positive.
Related Evidence
Bahan lain untuk Upper Respiratory Tract Infections
Vitamin C untuk kondisi lain
References
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