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Vitamin C cho Exercise-Induced Immune Suppression

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Research suggests regular vitamin C supplementation may reduce post-exercise URTI incidence in athletes, military personnel, and individuals under extreme physical stress. Benefits appear more pronounced in those exposed to severe physical stress.

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Kết luận

            
            
Research suggests regular vitamin C supplementation may reduce post-exercise URTI incidence in athletes, military personnel, and individuals under extreme physical stress. Benefits appear more pronounced in those exposed to severe physical stress.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
            
            

                
                Dose: None
                
                
                so với: None
                
                
                Outcome: Micronutrient deficiency management in pediatric IBD
                
                
                Hiệu quả: None
                
                
                None
                
            

            
            
Đối tượng nghiên cứu: Children with inflammatory bowel disease (review)

            
        

        
        

            

                
                    Randomized Controlled Trial
                
                
                
                
            

            
                Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some …
            
            

                
                Dose: None
                
                
                so với: Basal diet without supplementation
                
                
                Outcome: Antioxidant status, hematology, growth in broilers
                
                
                Hiệu quả: None
                
                
                None
                
            

            
            
Đối tượng nghiên cứu: Broiler chickens

            
        

        
        

            

                
                    Review
                
                
                n=26282
                
                
                988 weeks
                
                
            

            
                Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES.
            
            

                
                Dose: 45%
                
                
                so với: None
                
                
                Outcome: None
                
                
                Hiệu quả: None
                
                
                None
                
            

            
            
Đối tượng nghiên cứu: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Role of vitamins in gastrointestinal diseases.
            
            

                
                Dose: None
                
                
                so với: None
                
                
                Outcome: None
                
                
                Hiệu quả: None
                
                
                None
                
            

            
            
Đối tượng nghiên cứu: men

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Influence of mineral and vitamin supplements on pregnancy outcome.
            
            

                
                Dose: None
                
                
                so với: None
                
                
                Outcome: Pregnancy outcome (birth weight, preeclampsia, NTD)
                
                
                Hiệu quả: None
                
                
                None
                
            

            
            
Đối tượng nghiên cứu: Pregnant women

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                The immune system: a target for functional foods?
            
            

                
                Dose: Probiotics, prebiotics, fatty acids, vitamins
                
                
                so với: None
                
                
                Outcome: Immune system modulation by functional foods
                
                
                Hiệu quả: None
                
                
                None
                
            

            
            
Đối tượng nghiên cứu: General population

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
5

        
Nghiên cứu

    

    

        
600

        
Người tham gia

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Xếp hạng

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2025
                        
                        4 trích dẫn
                        
                    

                

                
                

                    

                        
                            Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some Immunoglobulins in Japanese Quail Under …
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        Biological trace element …
                        2022
                        
                        5 trích dẫn
                        
                    

                

                
                

                    

                        
                            Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2020
                        
                        75 trích dẫn
                        
                    

                

                
                

                    

                        
                            Role of vitamins in gastrointestinal diseases.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        World journal of …
                        2015
                        
                        62 trích dẫn
                        
                    

                

                
                

                    

                        
                            Influence of mineral and vitamin supplements on pregnancy outcome.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        European journal of …
                        2012
                        
                        225 trích dẫn
                        
                    

                

                
                

                    

                        
                            The immune system: a target for functional foods?
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        The British journal …
                        2002
                        
                        358 trích dẫn
                        
                    

                

                
                

                    

                        
                            Exercise immunology: nutritional countermeasures.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Canadian journal of …
                        2001
                        
                        72 trích dẫn
                        
                    

                

                
                

                    

                        
                            Is infection risk linked to exercise workload?
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Medicine and science …
                        2000
                        
                        262 trích dẫn
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Liều lượng thường dùng

                

                    
                    

                        
general:

                        
75-90 mg/day

                    

                    
                    

                        
acuteillness:

                        
1,000-2,000 mg/day

                    

                    
                    

                        
immunesupport:

                        
200-1,000 mg/day

                    

                    
                

                
                

                    Giới hạn trên: 2,000 mg/day
                

                
            

            

            
            

                
Liều lượng đã nghiên cứu

                

                    

                        
                            

                                Liều lượng
                                Thời gian
                                Hiệu quả
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                45%
                                988 weeks
                                
                                    
                                    Positive
                                    
                                
                                26282
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                Probiotics, prebiotics, fatty acids, vitamins
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                Vitamin C, E, glutamine, zinc
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                2.0 weeks
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Thời điểm dùng tốt nhất: With meals; divide doses >500 mg for better absorption
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Tác dụng phụ đã được báo cáo

                    
    
                        
                        
  • 
                            ⚠
                            Gastrointestinal distress (nausea, diarrhea, cramps) at high doses
                        
    • 
                        
                        
  • 
                            ⚠
                            Increased risk of kidney stones in susceptible individuals
                        
    • 
                        
                        
  • 
                            ⚠
                            Interference with certain lab tests (glucose, occult blood)
                        
    • 
                        
                        
  • 
                            ⚠
                            Iron overload risk in hemochromatosis patients
                        
    • 
                        
                    

                

                

                
                

                    
Tương tác đã biết

                    
    
                        
                        
  • 
                            ●
                            Enhances non-heme iron absorption (beneficial or harmful depending on iron status)
                        
    • 
                        
                        
  • 
                            ●
                            High doses may reduce effectiveness of certain chemotherapy agents
                        
    • 
                        
                        
  • 
                            ●
                            May interfere with anticoagulant therapy (warfarin) at high doses
                        
    • 
                        
                        
  • 
                            ●
                            Aluminum-containing antacids (increased aluminum absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        Mức hấp thụ tối đa cho phép: 2,000 mg/day
                    

                

                
            

            

                Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Vitamin C help with Exercise-Induced Immune Suppression?
            
        
        

            Based on 5 studies with 600 participants, there is moderate evidence from clinical studies that Vitamin C may support Exercise-Induced Immune Suppression management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Vitamin C should I take for Exercise-Induced Immune Suppression?
            
        
        

            Studies have used various dosages. A commonly studied range is 75-90 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Vitamin C?
            
        
        

            Reported side effects may include Gastrointestinal distress (nausea, diarrhea, cramps) at high doses, Increased risk of kidney stones in susceptible individuals, Interference with certain lab tests (glucose, occult blood), Iron overload risk in hemochromatosis patients. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Vitamin C and Exercise-Induced Immune Suppression?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
Các thành phần khác cho Exercise-Induced Immune Suppression

                    

                        
                        
                            Glutamine
                            B

                        
                        
                    

                

                

                
                

                    
Vitamin C cho các tình trạng khác

                    

                        
                        
                            Upper Respiratory Tract Infections
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Tiziana Galeazzi et al..
      Nutrients.
      2025.
      Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
      doi:10.3390/nu17091425
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Ahmed Gouda et al..
      Biol Trace Elem Res.
      2022.
      Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some Immunoglobulins in Japanese Quail Under …
      doi:10.1007/s12011-021-02884-y
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Carroll A Reider et al..
      Nutrients.
      2020.
      Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES.
      doi:10.3390/nu12061735
      PubMed
    
    4. 
    
    
  4. 
      [4]
      Omar A Masri et al..
      World J Gastroenterol.
      2015.
      Role of vitamins in gastrointestinal diseases.
      doi:10.3748/wjg.v21.i17.5191
      PubMed
    
    5. 
    
    
  5. 
      [5]
      Nils Hovdenak et al..
      Eur J Obstet Gynecol Reprod Biol.
      2012.
      Influence of mineral and vitamin supplements on pregnancy outcome.
      doi:10.1016/j.ejogrb.2012.06.020
      PubMed
    
    6. 
    
    
  6. 
      [6]
      Philip C Calder et al..
      Br J Nutr.
      2002.
      The immune system: a target for functional foods?
      doi:10.1079/BJN2002682
      PubMed
    
    7. 
    
    
  7. 
      [7]
      D C Nieman.
      Can J Appl Physiol.
      2001.
      Exercise immunology: nutritional countermeasures.
      doi:10.1139/h2001-041
      PubMed
    
    8. 
    
    
  8. 
      [8]
      D C Nieman.
      Med Sci Sports Exerc.
      2000.
      Is infection risk linked to exercise workload?
      doi:10.1097/00005768-200007001-00005
      PubMed
    
    9. 
    
  















    

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