Vitamin C ： Exercise-Induced Immune Suppression
B エビデンス 少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。Research suggests regular vitamin C supplementation may reduce post-exercise URTI incidence in athletes, military personnel, and individuals under extreme physical stress. Benefits appear more pronounced in those exposed to severe physical stress.
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B
結論
Research suggests regular vitamin C supplementation may reduce post-exercise URTI incidence in athletes, military personnel, and individuals under extreme physical stress. Benefits appear more pronounced in those exposed to severe physical stress.
Key Study Findings
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
効果: None
None
対象集団: Children with inflammatory bowel disease (review)
Randomized Controlled Trial
Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some …
Dose: None
vs: Basal diet without supplementation
Outcome: Antioxidant status, hematology, growth in broilers
効果: None
None
対象集団: Broiler chickens
Review
n=26282
988 weeks
Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES.
Dose: 45%
vs: None
Outcome: None
効果: None
None
対象集団: None
Review
Role of vitamins in gastrointestinal diseases.
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: men
Review
Influence of mineral and vitamin supplements on pregnancy outcome.
Dose: None
vs: None
Outcome: Pregnancy outcome (birth weight, preeclampsia, NTD)
効果: None
None
対象集団: Pregnant women
Review
The immune system: a target for functional foods?
Dose: Probiotics, prebiotics, fatty acids, vitamins
vs: None
Outcome: Immune system modulation by functional foods
効果: None
None
対象集団: General population
Key Statistics
5
研究数
600
参加者数
↑
Positive
B
グレード
Referenced Papers
Nutrients
2025
4 件の引用
Biological trace element …
2022
5 件の引用
Nutrients
2020
75 件の引用
World journal of …
2015
62 件の引用
European journal of …
2012
225 件の引用
The British journal …
2002
358 件の引用
Canadian journal of …
2001
72 件の引用
Medicine and science …
2000
262 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 75-90 mg/day
- acuteillness:
- 1,000-2,000 mg/day
- immunesupport:
- 200-1,000 mg/day
上限量： 2,000 mg/day
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| 45% | 988 weeks | Positive | 26282 |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| Probiotics, prebiotics, fatty acids, vitamins | -- | Positive | -- |
| Vitamin C, E, glutamine, zinc | -- | Positive | -- |
| None | 2.0 weeks | Mixed | -- |
推奨摂取タイミング： With meals; divide doses >500 mg for better absorption
Safety & Side Effects
報告されている副作用
- ⚠ Gastrointestinal distress (nausea, diarrhea, cramps) at high doses
- ⚠ Increased risk of kidney stones in susceptible individuals
- ⚠ Interference with certain lab tests (glucose, occult blood)
- ⚠ Iron overload risk in hemochromatosis patients
既知の相互作用
- ● Enhances non-heme iron absorption (beneficial or harmful depending on iron status)
- ● High doses may reduce effectiveness of certain chemotherapy agents
- ● May interfere with anticoagulant therapy (warfarin) at high doses
- ● Aluminum-containing antacids (increased aluminum absorption)
耐容上限摂取量： 2,000 mg/day
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does Vitamin C help with Exercise-Induced Immune Suppression?
Based on 5 studies with 600 participants, there is moderate evidence from clinical studies that Vitamin C may support Exercise-Induced Immune Suppression management. Our evidence grade is B (Good Evidence).
How much Vitamin C should I take for Exercise-Induced Immune Suppression?
Studies have used various dosages. A commonly studied range is 75-90 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin C?
Reported side effects may include Gastrointestinal distress (nausea, diarrhea, cramps) at high doses, Increased risk of kidney stones in susceptible individuals, Interference with certain lab tests (glucose, occult blood), Iron overload risk in hemochromatosis patients. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin C and Exercise-Induced Immune Suppression?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： Exercise-Induced Immune Suppression
Vitamin C 他の症状・状態について
References
- [1] Tiziana Galeazzi et al.. Nutrients. 2025. Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do? doi:10.3390/nu17091425 PubMed
- [2] Ahmed Gouda et al.. Biol Trace Elem Res. 2022. Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some Immunoglobulins in Japanese Quail Under … doi:10.1007/s12011-021-02884-y PubMed
- [3] Carroll A Reider et al.. Nutrients. 2020. Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES. doi:10.3390/nu12061735 PubMed
- [4] Omar A Masri et al.. World J Gastroenterol. 2015. Role of vitamins in gastrointestinal diseases. doi:10.3748/wjg.v21.i17.5191 PubMed
- [5] Nils Hovdenak et al.. Eur J Obstet Gynecol Reprod Biol. 2012. Influence of mineral and vitamin supplements on pregnancy outcome. doi:10.1016/j.ejogrb.2012.06.020 PubMed
- [6] Philip C Calder et al.. Br J Nutr. 2002. The immune system: a target for functional foods? doi:10.1079/BJN2002682 PubMed
- [7] D C Nieman. Can J Appl Physiol. 2001. Exercise immunology: nutritional countermeasures. doi:10.1139/h2001-041 PubMed
- [8] D C Nieman. Med Sci Sports Exerc. 2000. Is infection risk linked to exercise workload? doi:10.1097/00005768-200007001-00005 PubMed
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