Vitamin D для Upper Respiratory Tract Infections
A Доказательства Несколько крупных клинических испытаний стабильно демонстрируют значительные преимущества.Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.
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A
Итог
Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.
Key Study Findings
Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None
или: None
Outcome: None
Эффект: None
None
Популяция: Elite/professional cyclists nutrition review
Systematic Review
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Dose: Disease-modifying agents (tolvaptan, etc.)
или: Placebo or standard care
Outcome: Kidney disease progression
Эффект: None
None
Популяция: Patients with ADPKD
Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals
или: None
Outcome: Immune response modulation in COVID-19
Эффект: None
None
Популяция: COVID-19 patients with gut dysbiosis
Review
Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature.
Dose: 600-800 IU (DRI) or higher
или: None
Outcome: Skeletal and extra-skeletal health benefits
Эффект: None
None
Популяция: General population (guideline comparison)
Meta-Analysis
n=5748
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 …
Dose: 400 IU
или: Placebo
Outcome: None
Эффект: None
None
Популяция: Healthy adults
Case-Control
26.0 weeks
Vitamin D - An Elixir for Recurrent Upper Respiratory Tract Infection.
Dose: 98%
или: control
Outcome: None
Эффект: None
None
Популяция: None
Key Statistics
40
Исследования
30000
Участники
↑
Positive
A
Оценка
Referenced Papers
International journal of …
2025
2 цитирований
Endocrine practice : …
2024
24 цитирований
Nutrition reviews
2024
9 цитирований
Journal of translational …
2024
2 цитирований
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Systematic Review
The Cochrane database …
2024
1 цитирований
Indian journal of …
2023
Dermatologic therapy
2022
42 цитирований
Clinical nutrition (Edinburgh, …
2022
17 цитирований
Medicine and science …
2021
18 цитирований
Vitamin D and upper respiratory tract infections in young active males exposed to cold environments.
Other
Annals of agricultural …
2021
3 цитирований
The World Allergy …
2020
16 цитирований
Nutrients
2020
1 цитирований
The Pediatric infectious …
2019
15 цитирований
European archives of …
2019
14 цитирований
Association of the 25(OH) vitamin D status with upper respiratory tract infections morbidity in water sports elite athletes.
Observational
The Journal of …
2019
9 цитирований
Indian journal of …
2019
3 цитирований
International journal of …
2018
165 цитирований
International journal of …
2018
37 цитирований
The journal of …
2018
27 цитирований
JAMA
2017
131 цитирований
Public health nutrition
2017
6 цитирований
European journal of …
2016
93 цитирований
American journal of …
2016
45 цитирований
Journal of general …
2016
38 цитирований
International journal of …
2016
22 цитирований
Epidemiology and infection
2016
13 цитирований
[Changes in 25-hydroxyvitamin D3 level and its significance in children with Kawasaki disease].
Other
Zhongguo dang dai …
2016
5 цитирований
European journal of …
2016
BMC infectious diseases
2014
58 цитирований
Clinical infectious diseases …
2013
129 цитирований
Vitamin D3 supplementation and upper respiratory tract infections in a randomized, controlled trial.
RCT
Clinical infectious diseases …
2013
58 цитирований
Indian journal of …
2013
24 цитирований
Acta scientiarum polonorum. …
2012
11 цитирований
International journal of …
2011
49 цитирований
The Journal of …
2010
93 цитирований
Journal of the …
2010
11 цитирований
Archives of internal …
2009
975 цитирований
Clinical journal of …
2008
148 цитирований
International journal of …
2002
26 цитирований
Manometric study in Kearns-Sayre syndrome.
Case Report
Diseases of the …
2001
7 цитирований
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 600-800 IU/day
- immunesupport:
- 1,000-2,000 IU/day
- deficiencycorrection:
- 4,000-5,000 IU/day (under medical supervision)
Верхний предел: 4,000 IU/day (100 mcg)
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| Disease-modifying agents (tolvaptan, etc.) | -- | Positive | -- |
| Probiotics, nutraceuticals | -- | Positive | -- |
| 600-800 IU (DRI) or higher | -- | Positive | -- |
| 400 IU | -- | Negative | 5748 |
| 98% | 26.0 weeks | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 50554 |
Лучшее время приёма: With a meal containing fat for better absorption
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
- ⚠ Kidney stones with excessive long-term use
- ⚠ Constipation
- ⚠ Metallic taste
Известные взаимодействия
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
Допустимый верхний уровень потребления: 4,000 IU/day (100 mcg)
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Vitamin D help with Upper Respiratory Tract Infections?
Based on 40 studies with 30,000 participants, there is strong evidence from multiple clinical trials that Vitamin D may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).
How much Vitamin D should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Upper Respiratory Tract Infections?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 40 peer-reviewed studies with 30,000 total participants. The overall direction of effect is positive.
Related Evidence
Другие ингредиенты для Upper Respiratory Tract Infections
Vitamin D для других состояний
References
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