Skip to main content
ImmuneCited

Vitamin D لـ Upper Respiratory Tract Infections

A

Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'immunecited.com'; const params = 'ingredient\u003Dvitamin\u002Dd\u0026condition\u003Dupper\u002Drespiratory\u002Dinfections'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    

Widget powered by . Free, no account required.

A

الخلاصة

Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.

Key Study Findings

Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: Elite/professional cyclists nutrition review

Systematic Review
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Dose: Disease-modifying agents (tolvaptan, etc.) مقابل: Placebo or standard care Outcome: Kidney disease progression التأثير: None None

المجتمع المدروس: Patients with ADPKD

Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals مقابل: None Outcome: Immune response modulation in COVID-19 التأثير: None None

المجتمع المدروس: COVID-19 patients with gut dysbiosis

Review
Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature.
Dose: 600-800 IU (DRI) or higher مقابل: None Outcome: Skeletal and extra-skeletal health benefits التأثير: None None

المجتمع المدروس: General population (guideline comparison)

Meta-Analysis n=5748
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 …
Dose: 400 IU مقابل: Placebo Outcome: None التأثير: None None

المجتمع المدروس: Healthy adults

Case-Control 26.0 weeks
Vitamin D - An Elixir for Recurrent Upper Respiratory Tract Infection.
Dose: 98% مقابل: control Outcome: None التأثير: None None

المجتمع المدروس: None

Key Statistics

40

الدراسات

30000

المشاركون

Positive

A

التقييم

Referenced Papers

Endocrine practice : … 2024 24 اقتباسات
The Cochrane database … 2024 1 اقتباسات
Dermatologic therapy 2022 42 اقتباسات
International journal of … 2018 165 اقتباسات
European journal of … 2016 93 اقتباسات
American journal of … 2016 45 اقتباسات
Journal of general … 2016 38 اقتباسات
Indian journal of … 2013 24 اقتباسات
Acta scientiarum polonorum. … 2012 11 اقتباسات
International journal of … 2011 49 اقتباسات
The Journal of … 2010 93 اقتباسات
Journal of the … 2010 11 اقتباسات
International journal of … 2002 26 اقتباسات
Diseases of the … 2001 7 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
600-800 IU/day
immunesupport:
1,000-2,000 IU/day
deficiencycorrection:
4,000-5,000 IU/day (under medical supervision)

الحد الأعلى: 4,000 IU/day (100 mcg)

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
None -- Mixed --
Disease-modifying agents (tolvaptan, etc.) -- Positive --
Probiotics, nutraceuticals -- Positive --
600-800 IU (DRI) or higher -- Positive --
400 IU -- Negative 5748
98% 26.0 weeks Mixed --
None -- Positive --
None -- Positive 50554

أفضل وقت للتناول: With a meal containing fat for better absorption

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Hypercalcemia at very high doses (nausea, vomiting, weakness)
  • Kidney stones with excessive long-term use
  • Constipation
  • Metallic taste

التفاعلات المعروفة

  • Thiazide diuretics (may increase risk of hypercalcemia)
  • Corticosteroids (reduce vitamin D absorption and metabolism)
  • Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
  • Statins (vitamin D may affect statin metabolism)

الحد الأقصى المسموح به: 4,000 IU/day (100 mcg)

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Vitamin D help with Upper Respiratory Tract Infections?
Based on 40 studies with 30,000 participants, there is strong evidence from multiple clinical trials that Vitamin D may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).
How much Vitamin D should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Upper Respiratory Tract Infections?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 40 peer-reviewed studies with 30,000 total participants. The overall direction of effect is positive.

Related Evidence

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.