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Vitamin D pour Upper Respiratory Tract Infections

A

Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.

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En conclusion

Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.

Key Study Findings

Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None vs: None Outcome: None Effet: None None

Population: Elite/professional cyclists nutrition review

Systematic Review
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Dose: Disease-modifying agents (tolvaptan, etc.) vs: Placebo or standard care Outcome: Kidney disease progression Effet: None None

Population: Patients with ADPKD

Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals vs: None Outcome: Immune response modulation in COVID-19 Effet: None None

Population: COVID-19 patients with gut dysbiosis

Review
Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature.
Dose: 600-800 IU (DRI) or higher vs: None Outcome: Skeletal and extra-skeletal health benefits Effet: None None

Population: General population (guideline comparison)

Meta-Analysis n=5748
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 …
Dose: 400 IU vs: Placebo Outcome: None Effet: None None

Population: Healthy adults

Case-Control 26.0 weeks
Vitamin D - An Elixir for Recurrent Upper Respiratory Tract Infection.
Dose: 98% vs: control Outcome: None Effet: None None

Population: None

Key Statistics

40

Études

30000

Participants

Positive

A

Note

Referenced Papers

Endocrine practice : … 2024 24 citations
Dermatologic therapy 2022 42 citations
International journal of … 2018 165 citations
European journal of … 2016 93 citations
Journal of general … 2016 38 citations
Indian journal of … 2013 24 citations
Acta scientiarum polonorum. … 2012 11 citations
International journal of … 2011 49 citations
Diseases of the … 2001 7 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
600-800 IU/day
immunesupport:
1,000-2,000 IU/day
deficiencycorrection:
4,000-5,000 IU/day (under medical supervision)

Limite supérieure : 4,000 IU/day (100 mcg)

Posologies étudiées dans la recherche

Posologie Durée Effet N
None -- Mixed --
Disease-modifying agents (tolvaptan, etc.) -- Positive --
Probiotics, nutraceuticals -- Positive --
600-800 IU (DRI) or higher -- Positive --
400 IU -- Negative 5748
98% 26.0 weeks Mixed --
None -- Positive --
None -- Positive 50554

Moment optimal de prise : With a meal containing fat for better absorption

Safety & Side Effects

Effets indésirables signalés

  • Hypercalcemia at very high doses (nausea, vomiting, weakness)
  • Kidney stones with excessive long-term use
  • Constipation
  • Metallic taste

Interactions connues

  • Thiazide diuretics (may increase risk of hypercalcemia)
  • Corticosteroids (reduce vitamin D absorption and metabolism)
  • Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
  • Statins (vitamin D may affect statin metabolism)

Apport maximal tolérable : 4,000 IU/day (100 mcg)

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Vitamin D help with Upper Respiratory Tract Infections?
Based on 40 studies with 30,000 participants, there is strong evidence from multiple clinical trials that Vitamin D may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).
How much Vitamin D should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Upper Respiratory Tract Infections?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 40 peer-reviewed studies with 30,000 total participants. The overall direction of effect is positive.

Related Evidence

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.