Maitake Mushroom for Immune Aging (Immunosenescence)

Clinical studies suggest maitake MD-Fraction may enhance innate immune function. D-Fraction and MD-Fraction concentrated extracts have been studied as immunotherapy adjuncts and are licensed as cancer adjunctive treatment in Japan.

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'immunecited.com'; const params = 'ingredient\u003Dmaitake\u0026condition\u003Dimmunosenescence'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

The Bottom Line

Key Study Findings

Review

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.

Dose: Edible/medicinal mushroom extracts vs: None Outcome: Anti-cancer activity in breast cancer Effect: None None

Population: Breast cancer (in vitro/animal review)

Systematic Review

Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies.

Dose: Various medicinal mushroom extracts vs: Standard cancer treatment Outcome: Quality of life and immune markers Effect: None None

Population: Cancer patients (clinical studies 2010-2020)

Key Statistics

Studies

100

Participants

↑

Positive

Grade

Referenced Papers

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer. Review

International journal of … 2023 40 citations

Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Systematic Review

Current oncology reports 2023 27 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Commonly Used Dosages

general:: 1-3 g/day
mdfraction:: 35-70 mg/day MD-Fraction extract

Upper limit: No established UL

Dosages Studied in Research

Dosage	Duration	Effect	N
Edible/medicinal mushroom extracts	--	Positive	--
Various medicinal mushroom extracts	--	Positive	--

Best taken: With or without food

Safety & Side Effects

Reported Side Effects

⚠ Generally well tolerated
⚠ Mild gastrointestinal effects at high doses
⚠ Potential hypoglycemia

Known Interactions

● Diabetes medications (may lower blood sugar)
● Anticoagulants (may increase bleeding risk)
● Immunosuppressant medications (may counteract immunosuppression)

Tolerable upper intake: No established UL

Always consult your healthcare provider before starting any supplement.

Frequently Asked Questions

Does Maitake Mushroom help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Maitake Mushroom may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

How much Maitake Mushroom should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Maitake Mushroom?

Reported side effects may include Generally well tolerated, Mild gastrointestinal effects at high doses, Potential hypoglycemia. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Maitake Mushroom and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

Related Evidence

Other ingredients for Immune Aging (Immunosenescence)

Vitamin D B Vitamin E B Bifidobacterium lactis B Reishi Mushroom C Turkey Tail Mushroom C Cordyceps C

Quick Verdict

Evidence Strength52%

Moderate confidence

Study Breakdown

RCT (0)Meta (0)Other (3)

Compare Alternatives

See how other ingredients compare for this condition.

View all ingredients for Immune Aging (Immunosenescence)

Learn More

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.