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ImmuneCited

Chaga Mushroom ： Chronic Inflammation

D

Preclinical models show chaga triterpenes may reduce secretion of pro-inflammatory cytokines in macrophages. Beta-glucan polysaccharides demonstrate immunomodulatory activity in vitro. Robust human clinical trials are still needed to confirm benefits.

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            D

        

        

            
結論

            
            
Preclinical models show chaga triterpenes may reduce secretion of pro-inflammatory cytokines in macrophages. Beta-glucan polysaccharides demonstrate immunomodulatory activity in vitro. Robust human clinical trials are still needed to confirm benefits.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                
                2 weeks
                
                
                Double-blind
                
            

            
                Beet supplementation mitigates post-exercise inflammation.
            
            

                
                Dose: 212 mg
                
                
                vs: Placebo
                
                
                Outcome: Inflammatory markers
                
                
                効果: None
                
                
                p < 0.001
                
            

            
            
対象集団: None

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
研究数

    

    

        
50

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Beet supplementation mitigates post-exercise inflammation.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Frontiers in nutrition
                        2024
                        
                        8 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
500-1,500 mg extract/day

                    

                    
                    

                        
traditional:

                        
1-2 cups tea/day

                    

                    
                

                
                

                    上限量： No established UL; caution with blood thinners and kidney disease
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                212 mg
                                2 weeks
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： With or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Oxalate content may contribute to kidney stones
                        
    • 
                        
                        
  • 
                            ⚠
                            Hypoglycemia risk
                        
    • 
                        
                        
  • 
                            ⚠
                            Potential anticoagulant effects
                        
    • 
                        
                        
  • 
                            ⚠
                            Limited safety data for long-term use
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants and antiplatelet drugs (may increase bleeding risk)
                        
    • 
                        
                        
  • 
                            ●
                            Diabetes medications (may lower blood sugar)
                        
    • 
                        
                        
  • 
                            ●
                            Immunosuppressant medications (may counteract immunosuppression)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： No established UL; caution with blood thinners and kidney disease
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Chaga Mushroom help with Chronic Inflammation?
            
        
        

            Based on 3 studies with 50 participants, there is preliminary evidence that needs more research that Chaga Mushroom may support Chronic Inflammation management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Chaga Mushroom should I take for Chronic Inflammation?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,500 mg extract/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Chaga Mushroom?
            
        
        

            Reported side effects may include Oxalate content may contribute to kidney stones, Hypoglycemia risk, Potential anticoagulant effects, Limited safety data for long-term use. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Chaga Mushroom and Chronic Inflammation?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 50 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。