Cordyceps для Immune Aging (Immunosenescence)

Q: Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

Q: How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

A double-blind randomized controlled trial found Cordyceps mycelium extract showed 38.8% enhancement of NK cell cytotoxic activity after 8 weeks in healthy adults. Supports cell-mediated immunity and may enhance immune surveillance capacity.

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Итог

Key Study Findings

Review n=321

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in …

Dose: None или: None Outcome: None Эффект: None None

Популяция: healthy individuals aged 16-35 from 5 intervention studies (2017-2024)

Other

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo.

Dose: None или: LPS-induced lung injury mouse model vs control Outcome: Immune cell infiltration and inflammatory cytokines Эффект: None None

Популяция: LPS-induced lung injury mouse model

Controlled Clinical Trial n=24 3 weeks

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota …

Dose: 60 mg/kg in basal diet или: LPS-challenged control (basal diet only) Outcome: Colonic morphology and microbiota composition Эффект: None None

Популяция: Weaned castrated piglets challenged with LPS

Review

Ergogenic Aid by Cordyceps: Does It Work??

Dose: None или: None Outcome: None Эффект: None None

Популяция: Review of Cordyceps as ergogenic aid in human studies

In Vitro n=24

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on …

Dose: Cordycepin (CPN) or C. militaris extract (CME) или: Basal diet + LPS challenge Outcome: Liver injury markers and transcriptome changes Эффект: None None

Популяция: Weaned piglets (4 groups, n=6)

Randomized Controlled Trial 2 weeks Double-blind

Beet supplementation mitigates post-exercise inflammation.

Dose: 212 mg или: Placebo Outcome: Inflammatory markers Эффект: None p < 0.001

Популяция: None

Key Statistics

Исследования

100

Участники

↑

Positive

Оценка

Referenced Papers

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in Humans-A Narrative Review. Review

Nutrients 2026

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo. Other

Journal of microbiology … 2025 2 цитирований

Ergogenic Aid by Cordyceps: Does It Work?? Review

Current nutrition reports 2025 2 цитирований

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota and metabolite profiles. Other

Frontiers in immunology 2025 1 цитирований

Beet supplementation mitigates post-exercise inflammation. Other

Frontiers in nutrition 2024 8 цитирований

Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function. Other

BMC veterinary research 2024 7 цитирований

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on Acute Liver Injury Induced by … Other

Animals : an … 2024 1 цитирований

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer. Review

International journal of … 2023 40 цитирований

Exploring Edible Mushrooms for Diabetes: Unveiling Their Role in Prevention and Treatment. Review

Molecules (Basel, Switzerland) 2023 40 цитирований

Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Systematic Review

Current oncology reports 2023 27 цитирований

Cordyceps militaris extracts and cordycepin ameliorate type 2 diabetes mellitus by modulating the gut microbiota and metabolites. Other

Frontiers in pharmacology 2023 26 цитирований

Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation. Other

Cureus 2023 5 цитирований

A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease. Review

Integrative medicine (Encinitas, … 2023 2 цитирований

Medicinal Fungi with Antiviral Effect. Review

Molecules (Basel, Switzerland) 2022 34 цитирований

Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease. Review

Explore (New York, … 2022 34 цитирований

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic … Review

Molecules (Basel, Switzerland) 2020 153 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:: 1-3 g/day extract
immunesupport:: 1,000-3,000 mg standardized extract/day

Верхний предел: No established UL

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
None	--	Mixed	321
None	--	Positive	--
60 mg/kg in basal diet	3 weeks	Positive	24
None	--	Mixed	--
Cordycepin (CPN) or C. militaris extract (CME)	--	Positive	24
212 mg	2 weeks	Neutral	--
None	--	Positive	--
Mushroom extracts (various species)	--	Positive	--

Лучшее время приёма: Morning or early afternoon; with or without food

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Mild gastrointestinal discomfort
⚠ Dry mouth
⚠ Nausea (rare)
⚠ Potential interaction with autoimmune conditions

Известные взаимодействия

● Immunosuppressant medications (may counteract immunosuppression)
● Anticoagulants (may increase bleeding risk)
● Diabetes medications (may enhance blood sugar lowering)

Допустимый верхний уровень потребления: No established UL

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Immune Aging (Immunosenescence)

Vitamin D B Vitamin E B Bifidobacterium lactis B Reishi Mushroom C Turkey Tail Mushroom C Maitake Mushroom C

Краткий вывод

Evidence Strength52%

Moderate confidence

Разбор исследований

RCT (0)Meta (0)Other (3)

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