Cordyceps 用于 Immune Aging (Immunosenescence)

Q: Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

Q: How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

A double-blind randomized controlled trial found Cordyceps mycelium extract showed 38.8% enhancement of NK cell cytotoxic activity after 8 weeks in healthy adults. Supports cell-mediated immunity and may enhance immune surveillance capacity.

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结论

Key Study Findings

Review n=321

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in …

Dose: None vs: None Outcome: None 效果: None None

研究人群: healthy individuals aged 16-35 from 5 intervention studies (2017-2024)

Other

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo.

Dose: None vs: LPS-induced lung injury mouse model vs control Outcome: Immune cell infiltration and inflammatory cytokines 效果: None None

研究人群: LPS-induced lung injury mouse model

Controlled Clinical Trial n=24 3 weeks

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota …

Dose: 60 mg/kg in basal diet vs: LPS-challenged control (basal diet only) Outcome: Colonic morphology and microbiota composition 效果: None None

研究人群: Weaned castrated piglets challenged with LPS

Review

Ergogenic Aid by Cordyceps: Does It Work??

Dose: None vs: None Outcome: None 效果: None None

研究人群: Review of Cordyceps as ergogenic aid in human studies

In Vitro n=24

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on …

Dose: Cordycepin (CPN) or C. militaris extract (CME) vs: Basal diet + LPS challenge Outcome: Liver injury markers and transcriptome changes 效果: None None

研究人群: Weaned piglets (4 groups, n=6)

Randomized Controlled Trial 2 weeks Double-blind

Beet supplementation mitigates post-exercise inflammation.

Dose: 212 mg vs: Placebo Outcome: Inflammatory markers 效果: None p < 0.001

研究人群: None

Key Statistics

研究数量

100

受试者

↑

Positive

等级

Referenced Papers

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in Humans-A Narrative Review. Review

Nutrients 2026

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo. Other

Journal of microbiology … 2025 2 次引用

Ergogenic Aid by Cordyceps: Does It Work?? Review

Current nutrition reports 2025 2 次引用

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota and metabolite profiles. Other

Frontiers in immunology 2025 1 次引用

Beet supplementation mitigates post-exercise inflammation. Other

Frontiers in nutrition 2024 8 次引用

Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function. Other

BMC veterinary research 2024 7 次引用

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on Acute Liver Injury Induced by … Other

Animals : an … 2024 1 次引用

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer. Review

International journal of … 2023 40 次引用

Exploring Edible Mushrooms for Diabetes: Unveiling Their Role in Prevention and Treatment. Review

Molecules (Basel, Switzerland) 2023 40 次引用

Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Systematic Review

Current oncology reports 2023 27 次引用

Cordyceps militaris extracts and cordycepin ameliorate type 2 diabetes mellitus by modulating the gut microbiota and metabolites. Other

Frontiers in pharmacology 2023 26 次引用

Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation. Other

Cureus 2023 5 次引用

A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease. Review

Integrative medicine (Encinitas, … 2023 2 次引用

Medicinal Fungi with Antiviral Effect. Review

Molecules (Basel, Switzerland) 2022 34 次引用

Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease. Review

Explore (New York, … 2022 34 次引用

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic … Review

Molecules (Basel, Switzerland) 2020 153 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 1-3 g/day extract
immunesupport:: 1,000-3,000 mg standardized extract/day

上限： No established UL

研究中使用的剂量

剂量	持续时间	效果	N
None	--	Mixed	321
None	--	Positive	--
60 mg/kg in basal diet	3 weeks	Positive	24
None	--	Mixed	--
Cordycepin (CPN) or C. militaris extract (CME)	--	Positive	24
212 mg	2 weeks	Neutral	--
None	--	Positive	--
Mushroom extracts (various species)	--	Positive	--

最佳服用时间： Morning or early afternoon; with or without food

Safety & Side Effects

已报告的副作用

⚠ Mild gastrointestinal discomfort
⚠ Dry mouth
⚠ Nausea (rare)
⚠ Potential interaction with autoimmune conditions

已知相互作用

● Immunosuppressant medications (may counteract immunosuppression)
● Anticoagulants (may increase bleeding risk)
● Diabetes medications (may enhance blood sugar lowering)

可耐受最高摄入量： No established UL

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

Related Evidence

其他成分用于 Immune Aging (Immunosenescence)

Vitamin D B Vitamin E B Bifidobacterium lactis B Reishi Mushroom C Turkey Tail Mushroom C Maitake Mushroom C

快速结论

Evidence Strength52%

Moderate confidence

研究分析

RCT (0)Meta (0)Other (3)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于 Immune Aging (Immunosenescence)

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