Alleviation of autoimmune disease by dietary lipids containing omega-3 fatty acids.

D R Robinson

Review Rheumatic diseases clinics of North America 1991 19 次引用

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Study Design

研究类型: Review
研究人群: animal model

干预措施: Alleviation of autoimmune disease by dietary lipids containing omega-3 fatty acids. None
对照组: None
主要结局: lipid levels
效应方向: Positive
偏倚风险: Unclear

Abstract

Dietary marine lipids that are enriched in omega-3, or n-3, fatty acids reduce the severity of autoimmune glomerulonephritis in several inbred murine strains. The protective effect of dietary n-3 fatty acids is also seen with a rat model of immune-complex induced vasculopathy, but no protective effects were seen with autoimmune vasculitis in the MRL/lpr mouse or with type II collagen-induced arthritis in rats. Dietary n-3 fatty acids are potential therapeutic agents for the treatment of autoimmune diseases, but careful clinical trials with the purified forms of n-3 fatty acids are needed to determine the usefulness of this intervention.

简要概述

Dietary marine lipids that are enriched in omega-3, or n, fatty acids reduce the severity of autoimmune glomerulonephritis in several inbred murine strains and are potential therapeutic agents for the treatment of autoimmune diseases.

Used In Evidence Reviews

B Omega-3 Fatty Acids (EPA/DHA) 用于 Autoimmune Conditions

Alleviation of autoimmune disease by dietary lipids containing omega-3 fatty acids.

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Study Design

Abstract

简要概述

Used In Evidence Reviews

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