Curcumin for Chronic Inflammation

References

1. [1] Mahdieh Khoshakhlagh et al.. Arab J Gastroenterol. 2026. Therapeutic potential of curcumin against pancreatitis. doi:10.1016/j.ajg.2025.12.001 PubMed
2. [2] Monika Martiniakova et al.. Nutrients. 2025. Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus. doi:10.3390/nu17020275 PubMed
3. [3] Kazuhiko Nakadate et al.. Int J Mol Sci. 2025. Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. doi:10.3390/ijms26115206 PubMed
4. [4] Fadiyah Jadid Alanazi et al.. Pathol Res Pract. 2025. Pathological interplay of NF-κB and M1 macrophages in chronic inflammatory lung diseases. doi:10.1016/j.prp.2025.155903 PubMed
5. [5] Mohamed Ahmed. Immun Ageing. 2025. Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol. doi:10.1186/s12979-025-00522-y PubMed
6. [6] Sherif Hamidu et al.. J Aging Res. 2025. Modulating Ferroptosis in Aging: The Therapeutic Potential of Natural Products. doi:10.1155/jare/8832992 PubMed
7. [7] Mahsa Yavari et al.. Nutrients. 2025. Mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease: Effects of Polyphenols and Omega-3 Polyunsaturated Fatty Acids. doi:10.3390/nu17071203 PubMed
8. [8] Miriam Cerullo et al.. Nutrients. 2025. Curcumin Modulation of the Gut-Brain Axis for Neuroinflammation and Metabolic Disorders Prevention and Treatment. doi:10.3390/nu17091430 PubMed
9. [9] Toshiki Otoda et al.. Biomedicines. 2025. Lysosomal Stress in Cardiovascular Diseases: Therapeutic Potential of Cardiovascular Drugs and Future Directions. doi:10.3390/biomedicines13051053 PubMed
10. [10] Song Ding et al.. Mater Today Bio. 2025. Curcumin-loaded nanoscale coordination polymers for ROS scavenging and anti-inflammatory therapy in atherosclerosis. doi:10.1016/j.mtbio.2025.102152 PubMed
11. [11] A Jeong You et al.. Antioxidants (Basel). 2025. Oxidative Stress and Dietary Antioxidants in Head and Neck Cancer. doi:10.3390/antiox14050508 PubMed
12. [12] Fuyuan Lang et al.. Biology (Basel). 2025. Osteopontin in Chronic Inflammatory Diseases: Mechanisms, Biomarker Potential, and Therapeutic Strategies. doi:10.3390/biology14040428 PubMed
13. [13] Surya Nath Pandey et al.. Inflammopharmacology. 2025. Targeting NLRP3 inflammasome with curcumin: mechanisms and therapeutic promise in chronic inflammation. doi:10.1007/s10787-025-01926-4 PubMed
14. [14] Angela Falvino et al.. Int J Mol Sci. 2025. Which Approach to Choose to Counteract Musculoskeletal Aging? A Comprehensive Review on the Multiple Effects of Exercise. doi:10.3390/ijms26157573 PubMed
15. [15] Panagiotis Theodosis-Nobelos et al.. Curr Issues Mol Biol. 2025. Antioxidant Naturally Occurring Pleiotropically Acting Bioactive Compounds, as Polymeric Nanotherapeutics Against Autoimmune Diseases Progression. doi:10.3390/cimb47060411 PubMed
16. [16] Rajashree Patnaik et al.. Cells. 2025. Curcumin Inhibits Protease Activated Receptor 2-Induced ERK Phosphorylation Calcium Mobilization and Anti-Apoptotic Signaling in Inflammation-Driven Colorectal Cancer Cells. doi:10.3390/cells14181451 PubMed
17. [17] Yugal Goel et al.. PNAS Nexus. 2025. Targeting sickle cell pathobiology and pain with novel transdermal curcumin. doi:10.1093/pnasnexus/pgaf053 PubMed
18. [18] Lujie Zhu et al.. Int J Oncol. 2025. A perspective on the chemical structures and molecular mechanisms of curcumin and its derivatives and analogs in cancer treatment (Review). doi:10.3892/ijo.2025.5782 PubMed
19. [19] Yuhan Wang et al.. Front Immunol. 2025. Research progress on traditional Chinese medicine compounds in autoimmune-related skin diseases. doi:10.3389/fimmu.2025.1629288 PubMed
20. [20] Houriah Yasir Nukaly et al.. J Clin Med. 2024. Oral Lichen Planus: A Narrative Review Navigating Etiologies, Clinical Manifestations, Diagnostics, and Therapeutic Approaches. doi:10.3390/jcm13175280 PubMed
21. [21] Qin Yang et al.. Sci Rep. 2024. Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability. doi:10.1038/s41598-024-81034-5 PubMed
22. [22] Masoumeh Shamsi et al.. Iran J Pharm Res. 2024. Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin … doi:10.5812/ijpr-151428 PubMed
23. [23] Kitty St Pierre et al.. Cochrane Database Syst Rev. 2024. Interventions for preventing the progression of autosomal dominant polycystic kidney disease. doi:10.1002/14651858.CD010294.pub3 PubMed
24. [24] Jing Song et al.. Biomed Pharmacother. 2023. A comprehensive review on celastrol, triptolide and triptonide: Insights on their pharmacological activity, toxicity, combination therapy, new dosage form and … doi:10.1016/j.biopha.2023.114705 PubMed
25. [25] Elham Abdollahi et al.. Curr Mol Pharmacol. 2023. Immunomodulatory Therapeutic Effects of Curcumin on M1/M2 Macrophage Polarization in Inflammatory Diseases. doi:10.2174/1874467215666220324114624 PubMed
26. [26] Davide Decandia et al.. Int J Mol Sci. 2023. Dietary Protection against Cognitive Impairment, Neuroinflammation and Oxidative Stress in Alzheimer's Disease Animal Models of Lipopolysaccharide-Induced Inflammation. doi:10.3390/ijms24065921 PubMed
27. [27] Wenhao Weng et al.. Semin Cancer Biol. 2022. Curcumin and colorectal cancer: An update and current perspective on this natural medicine. doi:10.1016/j.semcancer.2020.02.011 PubMed
28. [28] Karen S Coutinho-Wolino et al.. Nutr Res. 2022. Bioactive compounds modulating Toll-like 4 receptor (TLR4)-mediated inflammation: pathways involved and future perspectives. doi:10.1016/j.nutres.2022.09.001 PubMed
29. [29] Antonia Cianciulli et al.. Molecules. 2022. Inflammaging and Brain: Curcumin and Its Beneficial Potential as Regulator of Microglia Activation. doi:10.3390/molecules27020341 PubMed
30. [30] Elizabeth A Tanner et al.. Altern Ther Health Med. 2022. Optimized Curcumin, Pomegranate Extract, and Methylsulfonylmethane Reduce Acute, Systemic Inflammatory Response to a Half-marathon Race. PubMed
31. [31] E V Shiсh et al.. Vopr Pitan. 2022. [Social jetlag: possibilities of micronutrient support]. doi:10.33029/0042-8833-2022-91-3-85-95 PubMed
32. [32] Vasiliki Zoi et al.. Biomedicines. 2021. The Role of Curcumin in Cancer Treatment. doi:10.3390/biomedicines9091086 PubMed
33. [33] Ibrahim Jantan et al.. J Nutr Biochem. 2021. Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways. doi:10.1016/j.jnutbio.2021.108634 PubMed
34. [34] Friedrich Leblhuber et al.. Nutrients. 2021. The Immunopathogenesis of Alzheimer's Disease Is Related to the Composition of Gut Microbiota. doi:10.3390/nu13020361 PubMed
35. [35] Rosaria Varì et al.. Nutrients. 2021. Obesity-Associated Inflammation: Does Curcumin Exert a Beneficial Role? doi:10.3390/nu13031021 PubMed
36. [36] X Liu et al.. Osteoarthritis Cartilage. 2021. Efficacy and safety of a supplement combination on hand pain among people with symptomatic hand osteoarthritis an internet-based, randomised clinical … doi:10.1016/j.joca.2021.01.011 PubMed
37. [37] Thit Mynster Kronborg et al.. Front Med (Lausanne). 2021. Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study. doi:10.3389/fmed.2021.718896 PubMed
38. [38] Brian K McFarlin et al.. Front Physiol. 2021. Dietary Polyphenol and Methylsulfonylmethane Supplementation Improves Immune, DAMP Signaling, and Inflammatory Responses During Recovery From All-Out Running Efforts. doi:10.3389/fphys.2021.712731 PubMed
39. [39] Vanessa Bianconi et al.. Adv Exp Med Biol. 2021. The Multifaceted Actions of Curcumin in Obesity. doi:10.1007/978-3-030-73234-9_6 PubMed
40. [40] Danica Michaličková et al.. Eur J Pharmacol. 2020. Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis. doi:10.1016/j.ejphar.2020.172973 PubMed
41. [41] Priyankar Dey. Pharmacol Res. 2020. Targeting gut barrier dysfunction with phytotherapies: Effective strategy against chronic diseases. doi:10.1016/j.phrs.2020.105135 PubMed
42. [42] Guangchi Sun et al.. Brain Res Bull. 2020. Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury. doi:10.1016/j.brainresbull.2020.05.009 PubMed
43. [43] Oleh Lushchak et al.. Geroscience. 2020. Nanodelivery of phytobioactive compounds for treating aging-associated disorders. doi:10.1007/s11357-019-00116-9 PubMed
44. [44] Renyi Wu et al.. Mol Carcinog. 2020. Epigenetics/epigenomics and prevention by curcumin of early stages of inflammatory-driven colon cancer. doi:10.1002/mc.23146 PubMed
45. [45] Bagher Farhood et al.. J Cell Physiol. 2019. Curcumin as an anti-inflammatory agent: Implications to radiotherapy and chemotherapy. doi:10.1002/jcp.27442 PubMed
46. [46] Kathryn Burge et al.. Int J Mol Sci. 2019. Curcumin and Intestinal Inflammatory Diseases: Molecular Mechanisms of Protection. doi:10.3390/ijms20081912 PubMed
47. [47] Kana Shimizu et al.. Eur Cardiol. 2019. Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases. doi:10.15420/ecr.2019.17.2 PubMed
48. [48] Saumik Biswas et al.. Front Endocrinol (Lausanne). 2019. Curcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of Diabetes. doi:10.3389/fendo.2019.00887 PubMed
49. [49] Subash Chandra Gupta et al.. Front Immunol. 2018. Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases. doi:10.3389/fimmu.2018.02160 PubMed
50. [50] Chitra Rajagopal et al.. Pharmacol Res. 2018. Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy. doi:10.1016/j.phrs.2017.12.034 PubMed
51. [51] Siddhartha S Ghosh et al.. Tissue Barriers. 2018. Curcumin-mediated regulation of intestinal barrier function: The mechanism underlying its beneficial effects. doi:10.1080/21688370.2018.1425085 PubMed
52. [52] Sathish Sundar Dhilip Kumar et al.. Molecules. 2018. Therapeutic Potential and Recent Advances of Curcumin in the Treatment of Aging-Associated Diseases. doi:10.3390/molecules23040835 PubMed
53. [53] Marjana Rahman Sarker et al.. Geroscience. 2018. Efficacy of curcumin for age-associated cognitive decline: a narrative review of preclinical and clinical studies. doi:10.1007/s11357-018-0017-z PubMed
54. [54] Umair Iqbal et al.. Am J Med Sci. 2018. Use of Curcumin in Achieving Clinical and Endoscopic Remission in Ulcerative Colitis: A Systematic Review and Meta-analysis. doi:10.1016/j.amjms.2018.06.023 PubMed
55. [55] Julia Christina Kuszewski et al.. Adv Nutr. 2018. Can Curcumin Counteract Cognitive Decline? Clinical Trial Evidence and Rationale for Combining ω-3 Fatty Acids with Curcumin. doi:10.1093/advances/nmx013 PubMed
56. [56] Ivan Carrera et al.. Curr Med Chem. 2018. Dopaminergic Neuroprotection with Atremorine in Parkinson´s Disease. doi:10.2174/0929867325666180410100559 PubMed
57. [57] Chandana Mohanty et al.. Drug Discov Today. 2017. Curcumin and its topical formulations for wound healing applications. doi:10.1016/j.drudis.2017.07.001 PubMed
58. [58] Morteza Ghandadi et al.. Curr Pharm Des. 2017. Curcumin: An Effective Inhibitor of Interleukin-6. doi:10.2174/1381612822666161006151605 PubMed
59. [59] Yong Zhang et al.. Sci China Life Sci. 2017. Prevention and treatment of cancer targeting chronic inflammation: research progress, potential agents, clinical studies and mechanisms. doi:10.1007/s11427-017-9047-4 PubMed
60. [60] Samantha L Gardener et al.. J Alzheimers Dis. 2016. Diet and Inflammation in Alzheimer's Disease and Related Chronic Diseases: A Review. doi:10.3233/JAD-150765 PubMed
61. [61] Yan He et al.. Molecules. 2015. Curcumin, inflammation, and chronic diseases: how are they linked? doi:10.3390/molecules20059183 PubMed
62. [62] Nadine Apetz et al.. CNS Neurol Disord Drug Targets. 2014. Natural compounds and plant extracts as therapeutics against chronic inflammation in Alzheimer's disease--a translational perspective. doi:10.2174/1871527313666140917110635 PubMed
63. [63] Matthew Barnett et al.. J Nutrigenet Nutrigenomics. 2014. Metabolomics and Proteomics, and What to Do with All These 'Omes': Insights from Nutrigenomic Investigations in New Zealand. doi:10.1159/000381349 PubMed
64. [64] Adeeb Shehzad et al.. Biofactors. 2013. Curcumin in inflammatory diseases. doi:10.1002/biof.1066 PubMed
65. [65] Peter G Bradford. Biofactors. 2013. Curcumin and obesity. doi:10.1002/biof.1074 PubMed
66. [66] Elena Talero et al.. Curr Pharm Des. 2012. Chemoprevention with phytonutrients and microalgae products in chronic inflammation and colon cancer. doi:10.2174/138161212802083725 PubMed
67. [67] Ling Zhao et al.. Nutr Rev. 2011. Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals. doi:10.1111/j.1753-4887.2011.00394.x PubMed
68. [68] D G Binion et al.. Gut. 2008. Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. doi:10.1136/gut.2008.152496 PubMed
69. [69] Saibal Biswas et al.. Mol Nutr Food Res. 2008. Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin. doi:10.1002/mnfr.200700259 PubMed
70. [70] Irfan Rahman et al.. Curr Drug Targets. 2006. Antioxidant therapeutic targets in COPD. doi:10.2174/138945006777435254 PubMed