What is the recommended dosage for Saccharomyces boulardii?

Acute: 250 mg 2x/day; General: 250-500 mg/day (5-10 billion CFU)

What are the side effects of Saccharomyces boulardii?

Potential side effects include: Mild bloating and gas, Rare: fungemia in severely immunocompromised or ICU patients with central lines, Constipation (rare).

What is Saccharomyces boulardii and how does it support immune health?

Saccharomyces boulardii is a probiotic yeast with extensive clinical evidence for gastrointestinal and immune support. It may help maintain gut barrier integrity, stimulate secretory IgA production, and modulate inflammatory responses in the intestinal mucosa.

What dosage of Saccharomyces boulardii has been used in studies?

Clinical trials have used S. boulardii at doses of 250–1,000 mg per day (equivalent to 5–10 billion CFU), typically for 1 to 4 weeks. It is one of the most extensively studied probiotic organisms for antibiotic-associated and infectious diarrhea.

What are the potential side effects of Saccharomyces boulardii?

S. boulardii is generally well tolerated. Mild flatulence may occur. It should be avoided in critically ill patients with central venous catheters due to a small risk of fungemia. Unlike bacterial probiotics, it is not affected by antibiotics.

Saccharomyces boulardii
Saccharomyces boulardii

probiotic

Juga dikenal sebagai: S. boulardii, Saccharomyces boulardii CNCM I-745

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About

Saccharomyces boulardii adalah ragi non-patogenik yang mendukung fungsi sawar imun usus, meningkatkan produksi IgA sekretori, serta memodelasi respons inflamasi. Secara unik, ragi ini resisten terhadap antibiotik sehingga dapat digunakan bersamaan dengan terapi antibiotik. Meta-analisis mendukung efektivitasnya untuk diare terkait antibiotik dan pencegahan Clostridioides difficile.

How It Works

Non-pathogenic yeast that supports intestinal immune barrier function; enhances secretory IgA production; uniquely antibiotic-resistant; neutralizes bacterial toxins and supports commensal flora recovery.

Evidence For Conditions

Kondisi	Peringkat	Studi	Peserta
Gut Immune Health	B	15	3000	Lihat →

Side Effects

Mild bloating and gas
Rare: fungemia in severely immunocompromised or ICU patients with central lines
Constipation (rare)

Drug & Supplement Interactions

Antifungal medications (will kill S. boulardii; do not combine)
Uniquely safe to use with antibiotics (inherent antibiotic resistance)

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Related Ingredients

Lactobacillus rhamnosus GG Bifidobacterium lactis

Fakta Singkat

Dosis: Acute: 250 mg 2x/day; General: 250-500 mg/day (5-10 billion CFU)
Bentuk Sediaan: capsule powder sachet
Sumber Alami: Lychee fruit skin, Mangosteen (natural source of the strain)
Batas Atas: No established UL
Waktu Terbaik: Can be taken with antibiotics (uniquely antibiotic-resistant)

Ringkasan Bukti

Gut Immune Health B

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