What is the recommended dosage for Omega-3 Fatty Acids (EPA/DHA)?

General: 250-500 mg combined EPA/DHA/day; Anti Inflammatory: 1,000-3,000 mg combined EPA/DHA/day

What are the side effects of Omega-3 Fatty Acids (EPA/DHA)?

Potential side effects include: Fishy aftertaste and burping, Gastrointestinal discomfort (nausea, diarrhea), Increased bleeding risk at high doses, Potential LDL cholesterol increase at very high doses.

What is omega-3 and how does it support immune function?

Omega-3 fatty acids (EPA and DHA) are essential polyunsaturated fats found in fish oil and algae. They play a role in resolving inflammation through specialized pro-resolving mediators (SPMs) and have been studied for their effects on immune cell membrane function.

What dosage of omega-3 has been studied for immune-related outcomes?

Clinical trials have used omega-3 doses of 1–4 g per day of combined EPA and DHA. For immune and anti-inflammatory outcomes, doses of 2–3 g per day are common, typically studied over periods of 8 to 16 weeks.

What are the potential side effects of omega-3 supplementation?

Common side effects include fishy aftertaste, burping, and mild gastrointestinal effects. High doses (above 3 g per day) may increase bleeding risk and should be discussed with a healthcare provider, especially before surgery or if taking anticoagulants.

Omega-3 Fatty Acids (EPA/DHA)
Omega-3 Fatty Acids (EPA/DHA)

fatty_acid

다른 이름: Fish Oil, Eicosapentaenoic Acid, Docosahexaenoic Acid, Marine Omega-3

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EPA and DHA alter cell membrane phospholipid composition and give rise to specialized pro-resolving mediators (resolvins, protectins, maresins) that actively resolve inflammation. The VITAL trial showed a 15% reduction in autoimmune disease risk. DHA showed stronger anti-inflammatory effects than EPA in randomized studies.

How It Works

EPA and DHA alter cell membrane phospholipid composition and give rise to specialized pro-resolving mediators (resolvins, protectins, maresins); EPA inhibits NF-kB activation; DHA suppresses pro-inflammatory gene expression.

Evidence For Conditions

건강 상태	등급	연구	참여자
Chronic Inflammation	A	30	30000	보기 →
Autoimmune Conditions	B	10	25000	보기 →

Side Effects

Fishy aftertaste and burping
Gastrointestinal discomfort (nausea, diarrhea)
Increased bleeding risk at high doses
Potential LDL cholesterol increase at very high doses

Drug & Supplement Interactions

Anticoagulants and antiplatelet drugs (may increase bleeding risk)
Blood pressure medications (additive blood pressure lowering)
Orlistat (may reduce omega-3 absorption)
Cyclosporine (may modify immunosuppressive effects)

복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.

Related Ingredients

Conjugated Linoleic Acid

핵심 정보

용량: General: 250-500 mg combined EPA/DHA/day; Anti_Inflammatory: 1,000-3,000 mg combined EPA/DHA/day
제형: softgel liquid capsule
천연 원료: Salmon, Mackerel, Sardines, Anchovies, Walnuts, Flaxseed
상한 섭취량: 3,000 mg/day EPA+DHA (FDA-recognized as safe)
권장 복용 시간: With meals

근거 요약

Chronic Inflammation A

Autoimmune Conditions B

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.