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Vitamin A لـ Pediatric Immune Support

B الأدلة تدعم ذلك تجربة عشوائية واحدة على الأقل، مع نتائج متسقة في معظمها.

Vitamin A supplementation in deficient children may significantly reduce morbidity and mortality from measles and diarrheal disease. No nutritional deficiency is more consistently associated with increased infectious disease susceptibility than vitamin A deficiency.

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الخلاصة

Vitamin A supplementation in deficient children may significantly reduce morbidity and mortality from measles and diarrheal disease. No nutritional deficiency is more consistently associated with increased infectious disease susceptibility than vitamin A deficiency.

Key Study Findings

Review n=26282 988 weeks
Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES.
Dose: 45% مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: None

Review
Diet and nutritional factors in inflammatory bowel diseases.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: IBD patients (diet and nutrition)

Observational Study n=61 260 weeks
Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease.
Dose: None مقابل: None Outcome: Vitamin and zinc status in IBD patients التأثير: None None

المجتمع المدروس: Patients with inflammatory bowel disease

Review
Influence of mineral and vitamin supplements on pregnancy outcome.
Dose: None مقابل: None Outcome: Pregnancy outcome (birth weight, preeclampsia, NTD) التأثير: None None

المجتمع المدروس: Pregnant women

Review
Cod liver oil, young children, and upper respiratory tract infections.
Dose: None مقابل: None Outcome: vitamin D levels التأثير: None None

المجتمع المدروس: children

Randomized Controlled Trial n=584 52 weeks Double-blind
Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: …
Dose: Zinc 20mg/day; VitA 20000-45000 IU every 2 months مقابل: Placebo Outcome: Interaction of zinc or vitamin A supplementation and … التأثير: None p<0.05

المجتمع المدروس: None

Key Statistics

10

الدراسات

5000

المشاركون

Positive

B

التقييم

Referenced Papers

World journal of … 2016 238 اقتباسات
European journal of … 2012 225 اقتباسات
Journal of the … 2010 11 اقتباسات
The British journal … 2002 358 اقتباسات
The Urologic clinics … 2002 20 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
700-900 mcg RAE/day
immunesupport:
900 mcg RAE/day

الحد الأعلى: 3,000 mcg RAE/day (preformed vitamin A)

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
45% 988 weeks Positive 26282
None -- Mixed --
None 260 weeks Positive 61
None -- Positive --
None -- Mixed --
Zinc 20mg/day; VitA 20000-45000 IU every 2 months 52 weeks Mixed 584
Probiotics, prebiotics, fatty acids, vitamins -- Positive --
Various nutrients (selenium, vitamins, green tea) -- Positive --

أفضل وقت للتناول: With meals containing fat

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Hepatotoxicity at chronic high doses
  • Birth defects (teratogenic at high doses during pregnancy)
  • Nausea and headache
  • Bone density reduction with long-term excess

التفاعلات المعروفة

  • Retinoid medications (additive toxicity risk)
  • Orlistat (reduces absorption of fat-soluble vitamins)
  • Alcohol (increases hepatotoxicity risk)
  • Tetracycline antibiotics (increased intracranial pressure risk)

الحد الأقصى المسموح به: 3,000 mcg RAE/day (preformed vitamin A)

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Vitamin A help with Pediatric Immune Support?
Based on 10 studies with 5,000 participants, there is moderate evidence from clinical studies that Vitamin A may support Pediatric Immune Support management. Our evidence grade is B (Good Evidence).
How much Vitamin A should I take for Pediatric Immune Support?
Studies have used various dosages. A commonly studied range is 700-900 mcg RAE/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin A?
Reported side effects may include Hepatotoxicity at chronic high doses, Birth defects (teratogenic at high doses during pregnancy), Nausea and headache, Bone density reduction with long-term excess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin A and Pediatric Immune Support?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 5,000 total participants. The overall direction of effect is positive.

مكونات أخرى لـ Pediatric Immune Support

References

  1. [1] Carroll A Reider et al.. Nutrients. 2020. Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES. doi:10.3390/nu12061735 PubMed
  2. [2] Danuta Owczarek et al.. World J Gastroenterol. 2016. Diet and nutritional factors in inflammatory bowel diseases. doi:10.3748/wjg.v22.i3.895 PubMed
  3. [3] Neha R Santucci et al.. J Pediatr Gastroenterol Nutr. 2014. Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease. doi:10.1097/MPG.0000000000000477 PubMed
  4. [4] Nils Hovdenak et al.. Eur J Obstet Gynecol Reprod Biol. 2012. Influence of mineral and vitamin supplements on pregnancy outcome. doi:10.1016/j.ejogrb.2012.06.020 PubMed
  5. [5] Linda A Linday. J Am Coll Nutr. 2010. Cod liver oil, young children, and upper respiratory tract infections. doi:10.1080/07315724.2010.10719894 PubMed
  6. [6] J L Rosado et al.. Eur J Clin Nutr. 2009. Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: a randomized clinical trial. doi:10.1038/ejcn.2009.53 PubMed
  7. [7] Philip C Calder et al.. Br J Nutr. 2002. The immune system: a target for functional foods? doi:10.1079/BJN2002682 PubMed
  8. [8] Ashish M Kamat et al.. Urol Clin North Am. 2002. Chemoprevention of bladder cancer. doi:10.1016/s0094-0143(02)00022-8 PubMed

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