Vitamin A для Pediatric Immune Support

Q: Does Vitamin A help with Pediatric Immune Support?

Based on 10 studies with 5,000 participants, there is moderate evidence from clinical studies that Vitamin A may support Pediatric Immune Support management. Our evidence grade is B (Good Evidence).

Q: How much Vitamin A should I take for Pediatric Immune Support?

Studies have used various dosages. A commonly studied range is 700-900 mcg RAE/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Vitamin A?

Reported side effects may include Hepatotoxicity at chronic high doses, Birth defects (teratogenic at high doses during pregnancy), Nausea and headache, Bone density reduction with long-term excess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Vitamin A and Pediatric Immune Support?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 5,000 total participants. The overall direction of effect is positive.

B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.

Vitamin A supplementation in deficient children may significantly reduce morbidity and mortality from measles and diarrheal disease. No nutritional deficiency is more consistently associated with increased infectious disease susceptibility than vitamin A deficiency.

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Итог

Key Study Findings

Review n=26282 988 weeks

Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES.

Dose: 45% или: None Outcome: None Эффект: None None

Популяция: None

Review

Diet and nutritional factors in inflammatory bowel diseases.

Dose: None или: None Outcome: None Эффект: None None

Популяция: IBD patients (diet and nutrition)

Observational Study n=61 260 weeks

Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease.

Dose: None или: None Outcome: Vitamin and zinc status in IBD patients Эффект: None None

Популяция: Patients with inflammatory bowel disease

Review

Influence of mineral and vitamin supplements on pregnancy outcome.

Dose: None или: None Outcome: Pregnancy outcome (birth weight, preeclampsia, NTD) Эффект: None None

Популяция: Pregnant women

Review

Cod liver oil, young children, and upper respiratory tract infections.

Dose: None или: None Outcome: vitamin D levels Эффект: None None

Популяция: children

Randomized Controlled Trial n=584 52 weeks Double-blind

Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: …

Dose: Zinc 20mg/day; VitA 20000-45000 IU every 2 months или: Placebo Outcome: Interaction of zinc or vitamin A supplementation and … Эффект: None p<0.05

Популяция: None

Key Statistics

Исследования

5000

Участники

↑

Positive

Оценка

Referenced Papers

Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES. Review

Nutrients 2020 75 цитирований

Diet and nutritional factors in inflammatory bowel diseases. Review

World journal of … 2016 238 цитирований

Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease. Other

Journal of pediatric … 2014 38 цитирований

Influence of mineral and vitamin supplements on pregnancy outcome. Review

European journal of … 2012 225 цитирований

Cod liver oil, young children, and upper respiratory tract infections. Review

Journal of the … 2010 11 цитирований

Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: a randomized clinical trial. RCT

European journal of … 2009 24 цитирований

The immune system: a target for functional foods? Review

The British journal … 2002 358 цитирований

Chemoprevention of bladder cancer. Review

The Urologic clinics … 2002 20 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:: 700-900 mcg RAE/day
immunesupport:: 900 mcg RAE/day

Верхний предел: 3,000 mcg RAE/day (preformed vitamin A)

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
45%	988 weeks	Positive	26282
None	--	Mixed	--
None	260 weeks	Positive	61
None	--	Positive	--
None	--	Mixed	--
Zinc 20mg/day; VitA 20000-45000 IU every 2 months	52 weeks	Mixed	584
Probiotics, prebiotics, fatty acids, vitamins	--	Positive	--
Various nutrients (selenium, vitamins, green tea)	--	Positive	--

Лучшее время приёма: With meals containing fat

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Hepatotoxicity at chronic high doses
⚠ Birth defects (teratogenic at high doses during pregnancy)
⚠ Nausea and headache
⚠ Bone density reduction with long-term excess

Известные взаимодействия

● Retinoid medications (additive toxicity risk)
● Orlistat (reduces absorption of fat-soluble vitamins)
● Alcohol (increases hepatotoxicity risk)
● Tetracycline antibiotics (increased intracranial pressure risk)

Допустимый верхний уровень потребления: 3,000 mcg RAE/day (preformed vitamin A)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Vitamin A help with Pediatric Immune Support?

Based on 10 studies with 5,000 participants, there is moderate evidence from clinical studies that Vitamin A may support Pediatric Immune Support management. Our evidence grade is B (Good Evidence).

How much Vitamin A should I take for Pediatric Immune Support?

Studies have used various dosages. A commonly studied range is 700-900 mcg RAE/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin A?

Reported side effects may include Hepatotoxicity at chronic high doses, Birth defects (teratogenic at high doses during pregnancy), Nausea and headache, Bone density reduction with long-term excess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin A and Pediatric Immune Support?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 5,000 total participants. The overall direction of effect is positive.

Другие ингредиенты для Pediatric Immune Support

Iron C

Краткий вывод

Evidence Strength72%

High confidence

Разбор исследований

RCT (1)Meta (0)Other (9)

Сравнить альтернативы

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References

[1] Carroll A Reider et al.. Nutrients. 2020. Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES. doi:10.3390/nu12061735 PubMed
[2] Danuta Owczarek et al.. World J Gastroenterol. 2016. Diet and nutritional factors in inflammatory bowel diseases. doi:10.3748/wjg.v22.i3.895 PubMed
[3] Neha R Santucci et al.. J Pediatr Gastroenterol Nutr. 2014. Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease. doi:10.1097/MPG.0000000000000477 PubMed
[4] Nils Hovdenak et al.. Eur J Obstet Gynecol Reprod Biol. 2012. Influence of mineral and vitamin supplements on pregnancy outcome. doi:10.1016/j.ejogrb.2012.06.020 PubMed
[5] Linda A Linday. J Am Coll Nutr. 2010. Cod liver oil, young children, and upper respiratory tract infections. doi:10.1080/07315724.2010.10719894 PubMed
[6] J L Rosado et al.. Eur J Clin Nutr. 2009. Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: a randomized clinical trial. doi:10.1038/ejcn.2009.53 PubMed
[7] Philip C Calder et al.. Br J Nutr. 2002. The immune system: a target for functional foods? doi:10.1079/BJN2002682 PubMed
[8] Ashish M Kamat et al.. Urol Clin North Am. 2002. Chemoprevention of bladder cancer. doi:10.1016/s0094-0143(02)00022-8 PubMed

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.

Vitamin A для Pediatric Immune Support

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Итог

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Часто используемые дозировки

Дозировки, изученные в исследованиях

Safety & Side Effects

Зарегистрированные побочные эффекты

Известные взаимодействия

Frequently Asked Questions

Related Evidence

Другие ингредиенты для Pediatric Immune Support

References