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Vitamin A 用于 Pediatric Immune Support

B

Vitamin A supplementation in deficient children may significantly reduce morbidity and mortality from measles and diarrheal disease. No nutritional deficiency is more consistently associated with increased infectious disease susceptibility than vitamin A deficiency.

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B

结论

Vitamin A supplementation in deficient children may significantly reduce morbidity and mortality from measles and diarrheal disease. No nutritional deficiency is more consistently associated with increased infectious disease susceptibility than vitamin A deficiency.

Key Study Findings

Review n=26282 988 weeks
Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES.
Dose: 45% vs: None Outcome: None 效果: None None

研究人群: None

Review
Diet and nutritional factors in inflammatory bowel diseases.
Dose: None vs: None Outcome: None 效果: None None

研究人群: IBD patients (diet and nutrition)

Observational Study n=61 260 weeks
Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease.
Dose: None vs: None Outcome: Vitamin and zinc status in IBD patients 效果: None None

研究人群: Patients with inflammatory bowel disease

Review
Influence of mineral and vitamin supplements on pregnancy outcome.
Dose: None vs: None Outcome: Pregnancy outcome (birth weight, preeclampsia, NTD) 效果: None None

研究人群: Pregnant women

Review
Cod liver oil, young children, and upper respiratory tract infections.
Dose: None vs: None Outcome: vitamin D levels 效果: None None

研究人群: children

Randomized Controlled Trial n=584 52 weeks Double-blind
Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: …
Dose: Zinc 20mg/day; VitA 20000-45000 IU every 2 months vs: Placebo Outcome: Interaction of zinc or vitamin A supplementation and … 效果: None p<0.05

研究人群: None

Key Statistics

10

研究数量

5000

受试者

Positive

B

等级

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:
700-900 mcg RAE/day
immunesupport:
900 mcg RAE/day

上限: 3,000 mcg RAE/day (preformed vitamin A)

研究中使用的剂量

剂量 持续时间 效果 N
45% 988 weeks Positive 26282
None -- Mixed --
None 260 weeks Positive 61
None -- Positive --
None -- Mixed --
Zinc 20mg/day; VitA 20000-45000 IU every 2 months 52 weeks Mixed 584
Probiotics, prebiotics, fatty acids, vitamins -- Positive --
Various nutrients (selenium, vitamins, green tea) -- Positive --

最佳服用时间: With meals containing fat

Safety & Side Effects

已报告的副作用

  • Hepatotoxicity at chronic high doses
  • Birth defects (teratogenic at high doses during pregnancy)
  • Nausea and headache
  • Bone density reduction with long-term excess

已知相互作用

  • Retinoid medications (additive toxicity risk)
  • Orlistat (reduces absorption of fat-soluble vitamins)
  • Alcohol (increases hepatotoxicity risk)
  • Tetracycline antibiotics (increased intracranial pressure risk)

可耐受最高摄入量: 3,000 mcg RAE/day (preformed vitamin A)

在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Vitamin A help with Pediatric Immune Support?
Based on 10 studies with 5,000 participants, there is moderate evidence from clinical studies that Vitamin A may support Pediatric Immune Support management. Our evidence grade is B (Good Evidence).
How much Vitamin A should I take for Pediatric Immune Support?
Studies have used various dosages. A commonly studied range is 700-900 mcg RAE/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin A?
Reported side effects may include Hepatotoxicity at chronic high doses, Birth defects (teratogenic at high doses during pregnancy), Nausea and headache, Bone density reduction with long-term excess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin A and Pediatric Immune Support?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 5,000 total participants. The overall direction of effect is positive.

Related Evidence

其他成分用于 Pediatric Immune Support

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