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Iron для Pediatric Immune Support

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Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.

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Итог

Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.

Key Study Findings

Review
Alopecia Areata: Understanding the Pathophysiology and Advancements in Treatment Modalities.
Dose: None или: None Outcome: None Эффект: None None

Популяция: None

Systematic Review and Meta-Analysis n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None или: Placebo Эффект: Standardized mean differences reported for each element and disease combination (specific values not None
In Vitro
Microenvironment-responsive recombinant collagen XVII-based composite microneedles for the treatment of androgenetic alopecia.
Dose: None или: Minoxidil Outcome: Hair regeneration in AGA mice Эффект: None None

Популяция: AGA mouse model

Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None или: None Outcome: Micronutrient deficiency management in pediatric IBD Эффект: None None

Популяция: Children with inflammatory bowel disease (review)

Other
Engineered polyphenol-keratin nanocarriers enhance probiotic delivery and ameliorate obese ulcerative colitis.
Dose: None или: Uncoated EcN and UC model mice Outcome: UC inflammation and probiotic intestinal retention Эффект: None None

Популяция: Obese C57 mice with DSS-induced UC

Review
Frontal Fibrosing Alopecia in Men: A Review of the Literature.
Dose: None или: None Outcome: None Эффект: None None

Популяция: Review of frontal fibrosing alopecia in men

Key Statistics

5

Исследования

400

Участники

Positive

C

Оценка

Referenced Papers

Journal of clinical … 2025 1 цитирований
International journal of … 2024 3 цитирований
The Cochrane database … 2024 1 цитирований
Clinical reviews in … 2021 304 цитирований
Dermatitis : contact, … 2019 7 цитирований
World journal of … 2016 238 цитирований
Deutsches Arzteblatt international 2016 99 цитирований
Digestive diseases (Basel, … 2016 41 цитирований
The Cochrane database … 2015 147 цитирований
Der Internist 2015
Journal of immunological … 2014 13 цитирований
European journal of … 2012 225 цитирований
Inflammatory bowel diseases 2012 224 цитирований
Sleep medicine reviews 2012 139 цитирований
Food and nutrition … 2009 122 цитирований
Pharmacoepidemiology and drug … 2009 22 цитирований
The Annals of … 2008 82 цитирований
The Israel Medical … 2008 61 цитирований
American journal of … 2007 61 цитирований
Premenstrual syndrome. Systematic Review
BMJ clinical evidence 2007
Cardiovascular research 2006 42 цитирований
Heart failure reviews 2006 22 цитирований
Journal of pediatric … 2006 7 цитирований
The British journal … 2002 358 цитирований
American journal of … 1999 226 цитирований
Dermatologic clinics 1998 121 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
8-18 mg/day
deficiency:
Per medical guidance based on ferritin levels

Верхний предел: 45 mg/day (elemental iron)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Mixed --
None -- Mixed 7014
None -- Positive --
None -- Neutral --
None -- Positive --
None -- Mixed --
Disease-modifying agents (tolvaptan, etc.) -- Positive --
None -- Positive --

Лучшее время приёма: On empty stomach with vitamin C for best absorption; avoid with calcium, coffee, or tea

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Constipation (most common)
  • Nausea and stomach cramps
  • Dark or black stools
  • Iron overload with excessive supplementation (hemochromatosis risk)

Известные взаимодействия

  • Calcium supplements and dairy (reduce iron absorption by 50-60%)
  • Proton pump inhibitors and H2 blockers (reduce absorption)
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Levothyroxine (iron reduces thyroid hormone absorption)

Допустимый верхний уровень потребления: 45 mg/day (elemental iron)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Iron help with Pediatric Immune Support?
Based on 5 studies with 400 participants, there is limited but promising evidence that Iron may support Pediatric Immune Support management. Our evidence grade is C (Some Evidence).
How much Iron should I take for Pediatric Immune Support?
Studies have used various dosages. A commonly studied range is 8-18 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Iron?
Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Iron and Pediatric Immune Support?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Pediatric Immune Support

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.