Iron cho Pediatric Immune Support
C Bằng chứng Bằng chứng hạn chế từ các nghiên cứu nhỏ, nhưng có một số tín hiệu tích cực.Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
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C
Kết luận
Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
Key Study Findings
Review
Alopecia Areata: Understanding the Pathophysiology and Advancements in Treatment Modalities.
Dose: None
so với: None
Outcome: None
Hiệu quả: None
None
Đối tượng nghiên cứu: None
Systematic Review and Meta-Analysis
n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None
so với: Placebo
Hiệu quả: Standardized mean differences reported for each element and disease combination (specific values not
None
In Vitro
Microenvironment-responsive recombinant collagen XVII-based composite microneedles for the treatment of androgenetic alopecia.
Dose: None
so với: Minoxidil
Outcome: Hair regeneration in AGA mice
Hiệu quả: None
None
Đối tượng nghiên cứu: AGA mouse model
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
so với: None
Outcome: Micronutrient deficiency management in pediatric IBD
Hiệu quả: None
None
Đối tượng nghiên cứu: Children with inflammatory bowel disease (review)
Other
Engineered polyphenol-keratin nanocarriers enhance probiotic delivery and ameliorate obese ulcerative colitis.
Dose: None
so với: Uncoated EcN and UC model mice
Outcome: UC inflammation and probiotic intestinal retention
Hiệu quả: None
None
Đối tượng nghiên cứu: Obese C57 mice with DSS-induced UC
Review
Frontal Fibrosing Alopecia in Men: A Review of the Literature.
Dose: None
so với: None
Outcome: None
Hiệu quả: None
None
Đối tượng nghiên cứu: Review of frontal fibrosing alopecia in men
Key Statistics
5
Nghiên cứu
400
Người tham gia
↑
Positive
C
Xếp hạng
Referenced Papers
Acta biomaterialia
2025
13 trích dẫn
Cureus
2025
8 trích dẫn
Nutrients
2025
4 trích dẫn
Colloids and surfaces. …
2025
4 trích dẫn
Journal of clinical …
2025
1 trích dẫn
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Meta-Analysis
Nutrition reviews
2025
Circadian light/dark cycle reversal exacerbates the progression of chronic kidney disease in mice.
Other
Journal of pineal …
2024
9 trích dẫn
International journal of …
2024
3 trích dẫn
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Systematic Review
The Cochrane database …
2024
1 trích dẫn
Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata.
Other
Northern clinics of …
2022
7 trích dẫn
Clinical reviews in …
2021
304 trích dẫn
Biomedicines
2021
27 trích dẫn
Endocrine-related cancer
2021
26 trích dẫn
BMC veterinary research
2021
24 trích dẫn
World journal of …
2021
10 trích dẫn
BMC nephrology
2021
2 trích dẫn
Journal of dairy …
2020
58 trích dẫn
Journal of clinical …
2019
13 trích dẫn
Dermatitis : contact, …
2019
7 trích dẫn
Diabetes, obesity & …
2017
69 trích dẫn
World journal of …
2016
238 trích dẫn
Deutsches Arzteblatt international
2016
99 trích dẫn
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
Review
Digestive diseases (Basel, …
2016
41 trích dẫn
Annals of dermatology
2016
27 trích dẫn
Journal of sports …
2016
13 trích dẫn
Neuromolecular medicine
2016
The Cochrane database …
2015
147 trích dẫn
Der Internist
2015
Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine.
Review
Journal of immunological …
2014
13 trích dẫn
International journal of …
2013
104 trích dẫn
European journal of …
2012
225 trích dẫn
Inflammatory bowel diseases
2012
224 trích dẫn
Sleep medicine reviews
2012
139 trích dẫn
Food and nutrition …
2009
122 trích dẫn
Pharmacoepidemiology and drug …
2009
22 trích dẫn
The Annals of …
2008
82 trích dẫn
The Israel Medical …
2008
61 trích dẫn
American journal of …
2007
61 trích dẫn
Premenstrual syndrome.
Systematic Review
BMJ clinical evidence
2007
Cardiovascular research
2006
42 trích dẫn
Clinical and experimental …
2006
22 trích dẫn
Heart failure reviews
2006
22 trích dẫn
Journal of pediatric …
2006
7 trích dẫn
The British journal …
2002
358 trích dẫn
Unsafe and potentially safe herbal therapies.
Meta-Analysis
American journal of …
1999
226 trích dẫn
Dermatologic clinics
1998
121 trích dẫn
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Liều lượng thường dùng
- general:
- 8-18 mg/day
- deficiency:
- Per medical guidance based on ferritin levels
Giới hạn trên: 45 mg/day (elemental iron)
Liều lượng đã nghiên cứu
| Liều lượng | Thời gian | Hiệu quả | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | 7014 |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| Disease-modifying agents (tolvaptan, etc.) | -- | Positive | -- |
| None | -- | Positive | -- |
Thời điểm dùng tốt nhất: On empty stomach with vitamin C for best absorption; avoid with calcium, coffee, or tea
Safety & Side Effects
Tác dụng phụ đã được báo cáo
- ⚠ Constipation (most common)
- ⚠ Nausea and stomach cramps
- ⚠ Dark or black stools
- ⚠ Iron overload with excessive supplementation (hemochromatosis risk)
Tương tác đã biết
- ● Calcium supplements and dairy (reduce iron absorption by 50-60%)
- ● Proton pump inhibitors and H2 blockers (reduce absorption)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Levothyroxine (iron reduces thyroid hormone absorption)
Mức hấp thụ tối đa cho phép: 45 mg/day (elemental iron)
Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.
Frequently Asked Questions
Does Iron help with Pediatric Immune Support?
Based on 5 studies with 400 participants, there is limited but promising evidence that Iron may support Pediatric Immune Support management. Our evidence grade is C (Some Evidence).
How much Iron should I take for Pediatric Immune Support?
Studies have used various dosages. A commonly studied range is 8-18 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Iron?
Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Iron and Pediatric Immune Support?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
Related Evidence
Các thành phần khác cho Pediatric Immune Support
References
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