Iron için Pediatric Immune Support
C Kanıt Küçük çalışmalardan sınırlı kanıt mevcuttur, ancak bazı olumlu sinyaller bulunmaktadır.Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
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C
Sonuç
Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
Key Study Findings
Review
Alopecia Areata: Understanding the Pathophysiology and Advancements in Treatment Modalities.
Dose: None
vs: None
Outcome: None
Etki: None
None
Popülasyon: None
Systematic Review and Meta-Analysis
n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None
vs: Placebo
Etki: Standardized mean differences reported for each element and disease combination (specific values not
None
In Vitro
Microenvironment-responsive recombinant collagen XVII-based composite microneedles for the treatment of androgenetic alopecia.
Dose: None
vs: Minoxidil
Outcome: Hair regeneration in AGA mice
Etki: None
None
Popülasyon: AGA mouse model
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
Etki: None
None
Popülasyon: Children with inflammatory bowel disease (review)
Other
Engineered polyphenol-keratin nanocarriers enhance probiotic delivery and ameliorate obese ulcerative colitis.
Dose: None
vs: Uncoated EcN and UC model mice
Outcome: UC inflammation and probiotic intestinal retention
Etki: None
None
Popülasyon: Obese C57 mice with DSS-induced UC
Review
Frontal Fibrosing Alopecia in Men: A Review of the Literature.
Dose: None
vs: None
Outcome: None
Etki: None
None
Popülasyon: Review of frontal fibrosing alopecia in men
Key Statistics
5
Çalışmalar
400
Katılımcılar
↑
Positive
C
Derece
Referenced Papers
Acta biomaterialia
2025
13 atıf
Cureus
2025
8 atıf
Nutrients
2025
4 atıf
Colloids and surfaces. …
2025
4 atıf
Journal of clinical …
2025
1 atıf
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Meta-Analysis
Nutrition reviews
2025
Circadian light/dark cycle reversal exacerbates the progression of chronic kidney disease in mice.
Other
Journal of pineal …
2024
9 atıf
International journal of …
2024
3 atıf
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Systematic Review
The Cochrane database …
2024
1 atıf
Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata.
Other
Northern clinics of …
2022
7 atıf
Clinical reviews in …
2021
304 atıf
Biomedicines
2021
27 atıf
Endocrine-related cancer
2021
26 atıf
BMC veterinary research
2021
24 atıf
World journal of …
2021
10 atıf
BMC nephrology
2021
2 atıf
Journal of dairy …
2020
58 atıf
Journal of clinical …
2019
13 atıf
Dermatitis : contact, …
2019
7 atıf
Diabetes, obesity & …
2017
69 atıf
World journal of …
2016
238 atıf
Deutsches Arzteblatt international
2016
99 atıf
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
Review
Digestive diseases (Basel, …
2016
41 atıf
Annals of dermatology
2016
27 atıf
Journal of sports …
2016
13 atıf
Neuromolecular medicine
2016
The Cochrane database …
2015
147 atıf
Der Internist
2015
Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine.
Review
Journal of immunological …
2014
13 atıf
International journal of …
2013
104 atıf
European journal of …
2012
225 atıf
Inflammatory bowel diseases
2012
224 atıf
Sleep medicine reviews
2012
139 atıf
Food and nutrition …
2009
122 atıf
Pharmacoepidemiology and drug …
2009
22 atıf
The Annals of …
2008
82 atıf
The Israel Medical …
2008
61 atıf
American journal of …
2007
61 atıf
Premenstrual syndrome.
Systematic Review
BMJ clinical evidence
2007
Cardiovascular research
2006
42 atıf
Clinical and experimental …
2006
22 atıf
Heart failure reviews
2006
22 atıf
Journal of pediatric …
2006
7 atıf
The British journal …
2002
358 atıf
Unsafe and potentially safe herbal therapies.
Meta-Analysis
American journal of …
1999
226 atıf
Dermatologic clinics
1998
121 atıf
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Yaygın Kullanılan Dozajlar
- general:
- 8-18 mg/day
- deficiency:
- Per medical guidance based on ferritin levels
Üst sınır: 45 mg/day (elemental iron)
Araştırmalarda İncelenen Dozajlar
| Dozaj | Süre | Etki | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | 7014 |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| Disease-modifying agents (tolvaptan, etc.) | -- | Positive | -- |
| None | -- | Positive | -- |
En iyi alım zamanı: On empty stomach with vitamin C for best absorption; avoid with calcium, coffee, or tea
Safety & Side Effects
Bildirilen Yan Etkiler
- ⚠ Constipation (most common)
- ⚠ Nausea and stomach cramps
- ⚠ Dark or black stools
- ⚠ Iron overload with excessive supplementation (hemochromatosis risk)
Bilinen Etkileşimler
- ● Calcium supplements and dairy (reduce iron absorption by 50-60%)
- ● Proton pump inhibitors and H2 blockers (reduce absorption)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Levothyroxine (iron reduces thyroid hormone absorption)
Tolere edilebilir üst alım: 45 mg/day (elemental iron)
Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
Frequently Asked Questions
Does Iron help with Pediatric Immune Support?
Based on 5 studies with 400 participants, there is limited but promising evidence that Iron may support Pediatric Immune Support management. Our evidence grade is C (Some Evidence).
How much Iron should I take for Pediatric Immune Support?
Studies have used various dosages. A commonly studied range is 8-18 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Iron?
Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Iron and Pediatric Immune Support?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
Related Evidence
Şu durum için diğer içerikler: Pediatric Immune Support
References
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