Iron 관련 Pediatric Immune Support
CIron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
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C
결론
Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
Key Study Findings
Review
Alopecia Areata: Understanding the Pathophysiology and Advancements in Treatment Modalities.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
Systematic Review and Meta-Analysis
n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None
vs: Placebo
효과: Standardized mean differences reported for each element and disease combination (specific values not
None
In Vitro
Microenvironment-responsive recombinant collagen XVII-based composite microneedles for the treatment of androgenetic alopecia.
Dose: None
vs: Minoxidil
Outcome: Hair regeneration in AGA mice
효과: None
None
대상 집단: AGA mouse model
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
효과: None
None
대상 집단: Children with inflammatory bowel disease (review)
Other
Engineered polyphenol-keratin nanocarriers enhance probiotic delivery and ameliorate obese ulcerative colitis.
Dose: None
vs: Uncoated EcN and UC model mice
Outcome: UC inflammation and probiotic intestinal retention
효과: None
None
대상 집단: Obese C57 mice with DSS-induced UC
Review
Frontal Fibrosing Alopecia in Men: A Review of the Literature.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Review of frontal fibrosing alopecia in men
Key Statistics
5
연구
400
참여자
↑
Positive
C
등급
Referenced Papers
Acta biomaterialia
2025
13 인용
Cureus
2025
8 인용
Nutrients
2025
4 인용
Colloids and surfaces. …
2025
4 인용
Journal of clinical …
2025
1 인용
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Meta-Analysis
Nutrition reviews
2025
Circadian light/dark cycle reversal exacerbates the progression of chronic kidney disease in mice.
Other
Journal of pineal …
2024
9 인용
International journal of …
2024
3 인용
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Systematic Review
The Cochrane database …
2024
1 인용
Retrospective evaluation of clinical profile and comorbidities in patients with alopecia areata.
Other
Northern clinics of …
2022
7 인용
Clinical reviews in …
2021
304 인용
Biomedicines
2021
27 인용
Endocrine-related cancer
2021
26 인용
BMC veterinary research
2021
24 인용
World journal of …
2021
10 인용
BMC nephrology
2021
2 인용
Journal of dairy …
2020
58 인용
Journal of clinical …
2019
13 인용
Dermatitis : contact, …
2019
7 인용
Diabetes, obesity & …
2017
69 인용
World journal of …
2016
238 인용
Deutsches Arzteblatt international
2016
99 인용
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
Review
Digestive diseases (Basel, …
2016
41 인용
Annals of dermatology
2016
27 인용
Journal of sports …
2016
13 인용
Neuromolecular medicine
2016
The Cochrane database …
2015
147 인용
Der Internist
2015
Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine.
Review
Journal of immunological …
2014
13 인용
International journal of …
2013
104 인용
European journal of …
2012
225 인용
Inflammatory bowel diseases
2012
224 인용
Sleep medicine reviews
2012
139 인용
Food and nutrition …
2009
122 인용
Pharmacoepidemiology and drug …
2009
22 인용
The Annals of …
2008
82 인용
The Israel Medical …
2008
61 인용
American journal of …
2007
61 인용
Premenstrual syndrome.
Systematic Review
BMJ clinical evidence
2007
Cardiovascular research
2006
42 인용
Clinical and experimental …
2006
22 인용
Heart failure reviews
2006
22 인용
Journal of pediatric …
2006
7 인용
The British journal …
2002
358 인용
Unsafe and potentially safe herbal therapies.
Meta-Analysis
American journal of …
1999
226 인용
Dermatologic clinics
1998
121 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 8-18 mg/day
- deficiency:
- Per medical guidance based on ferritin levels
상한량: 45 mg/day (elemental iron)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | 7014 |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| Disease-modifying agents (tolvaptan, etc.) | -- | Positive | -- |
| None | -- | Positive | -- |
권장 복용 시간: On empty stomach with vitamin C for best absorption; avoid with calcium, coffee, or tea
Safety & Side Effects
보고된 부작용
- ⚠ Constipation (most common)
- ⚠ Nausea and stomach cramps
- ⚠ Dark or black stools
- ⚠ Iron overload with excessive supplementation (hemochromatosis risk)
알려진 상호작용
- ● Calcium supplements and dairy (reduce iron absorption by 50-60%)
- ● Proton pump inhibitors and H2 blockers (reduce absorption)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Levothyroxine (iron reduces thyroid hormone absorption)
일일 최대 섭취 허용량: 45 mg/day (elemental iron)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Iron help with Pediatric Immune Support?
Based on 5 studies with 400 participants, there is limited but promising evidence that Iron may support Pediatric Immune Support management. Our evidence grade is C (Some Evidence).
How much Iron should I take for Pediatric Immune Support?
Studies have used various dosages. A commonly studied range is 8-18 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Iron?
Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Iron and Pediatric Immune Support?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: Pediatric Immune Support
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