Iron for Pediatric Immune Support
CIron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
The Bottom Line
Iron supplementation in deficient children may help restore lymphocyte and neutrophil function. However, excess iron may feed pathogens and worsen infections. Supplementation should be guided by documented deficiency status.
Key Study Findings
Population: None
Population: AGA mouse model
Population: Children with inflammatory bowel disease (review)
Population: Obese C57 mice with DSS-induced UC
Population: Review of frontal fibrosing alopecia in men
Key Statistics
5
Studies
400
Participants
Positive
Grade
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Commonly Used Dosages
- general:
- 8-18 mg/day
- deficiency:
- Per medical guidance based on ferritin levels
Upper limit: 45 mg/day (elemental iron)
Dosages Studied in Research
| Dosage | Duration | Effect | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | 7014 |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| Disease-modifying agents (tolvaptan, etc.) | -- | Positive | -- |
| None | -- | Positive | -- |
Best taken: On empty stomach with vitamin C for best absorption; avoid with calcium, coffee, or tea
Safety & Side Effects
Reported Side Effects
- ⚠ Constipation (most common)
- ⚠ Nausea and stomach cramps
- ⚠ Dark or black stools
- ⚠ Iron overload with excessive supplementation (hemochromatosis risk)
Known Interactions
- ● Calcium supplements and dairy (reduce iron absorption by 50-60%)
- ● Proton pump inhibitors and H2 blockers (reduce absorption)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Levothyroxine (iron reduces thyroid hormone absorption)
Tolerable upper intake: 45 mg/day (elemental iron)
Always consult your healthcare provider before starting any supplement.
Frequently Asked Questions
Does Iron help with Pediatric Immune Support?
How much Iron should I take for Pediatric Immune Support?
Are there side effects of Iron?
How strong is the evidence for Iron and Pediatric Immune Support?
Related Evidence
Other ingredients for Pediatric Immune Support
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.