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Anti-inflammatory cytokine and M2 macrophage marker expression in D-galactose-aged macrophages following BB-12 treatment. Upregulation of IL-10 and arginase-1 suggests the probiotic promotes M2 macrophage polarization in aged immune cells.

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![Figure 5: Anti-inflammatory cytokine and M2 macrophage marker expression in D-galactose-aged macrophages following BB-12 treatment. Upregulation of IL-10 and arginase-1 suggests the probiotic promotes M2 macrophage polarization in aged immune cells.]()

> Source: Da-Yong Zhang et al. "Bifidobacterium lactis BB-12 Attenuates Macrophage Aging Induced by D-Galactose ." *Journal of immunology research*, 2019. PMID: [31930149](https://pubmed.ncbi.nlm.nih.gov/31930149/)
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  <img src="" alt="Anti-inflammatory cytokine and M2 macrophage marker expression in D-galactose-aged macrophages following BB-12 treatment. Upregulation of IL-10 and arginase-1 suggests the probiotic promotes M2 macrophage polarization in aged immune cells." />
  <figcaption>Figure 5. Anti-inflammatory cytokine and M2 macrophage marker expression in D-galactose-aged macrophages following BB-12 treatment. Upregulation of IL-10 and arginase-1 suggests the probiotic promotes M2 macrophage polarization in aged immune cells.<br>  Source: Da-Yong Zhang et al. "Bifidobacterium lactis BB-12 Attenuates Macrophage Aging Induced by D-Galactose ." <em>Journal of immunology research</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/31930149/">31930149</a></figcaption>
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