Zinc untuk Upper Respiratory Tract Infections
AMeta-analysis of 7 trials demonstrates zinc lozenges at 75+ mg/day may reduce cold duration by 33% when started within 24 hours of symptom onset. Zinc acetate lozenges at 80-92 mg/day showed 40% duration reduction. Doses below 75 mg/day showed no effect.
Kesimpulan
Meta-analysis of 7 trials demonstrates zinc lozenges at 75+ mg/day may reduce cold duration by 33% when started within 24 hours of symptom onset. Zinc acetate lozenges at 80-92 mg/day showed 40% duration reduction. Doses below 75 mg/day showed no effect.
Key Study Findings
Populasi: patients with post-viral olfactory dysfunction (non-COVID)
Populasi: None
Populasi: Elite/professional cyclists nutrition review
Populasi: Children/adolescents with undernutrition
Populasi: Children with otitis media
Populasi: respiratory disease
Key Statistics
15
Studi
1500
Peserta
Positive
Peringkat
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 8-11 mg/day
- coldtreatment:
- 75-100 mg/day elemental zinc (lozenges, within 24h of onset, up to 2 weeks)
- immunesupport:
- 15-30 mg/day
Batas atas: 40 mg/day (long-term)
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| tokishakuyakusan, zinc sulfate, methylcobalamin | -- | Positive | 107 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| Various oral nutritional supplements | -- | Positive | -- |
| 20 or 30 days treatment | 5 weeks | Positive | 120 |
| 31 μg | -- | Neutral | -- |
| 94.57% | -- | Mixed | -- |
| None | -- | Mixed | 387 |
Waktu terbaik diminum: Lozenges: dissolve slowly in mouth every 2-3h at cold onset; Supplements: with food to minimize nausea
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Nausea and vomiting (especially on an empty stomach)
- ⚠ Metallic taste in the mouth
- ⚠ Copper depletion with chronic high-dose use (>40 mg/day)
- ⚠ Headache and diarrhea
Interaksi yang Diketahui
- ● Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)
- ● Iron supplements (mutual absorption interference when taken together)
Asupan atas yang dapat ditoleransi: 40 mg/day (long-term)
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Zinc help with Upper Respiratory Tract Infections?
How much Zinc should I take for Upper Respiratory Tract Infections?
Are there side effects of Zinc?
How strong is the evidence for Zinc and Upper Respiratory Tract Infections?
Related Evidence
Bahan lain untuk Upper Respiratory Tract Infections
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