Endocrine risk factors for COVID-19 in context of aging.

L Máčová, M Bičíková, R Hampl

Review Physiological research 2021 2 件の引用

<\/script>\n

`; }, get iframeSnippet() { const domain = 'immunecited.com'; const params = 'pmid\u003D34913349'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

Study Design

研究タイプ: Review
対象集団: impairment of disorder

介入: Endocrine risk factors for COVID-19 in context of aging. None
比較対照: None
主要アウトカム: None
効果の方向: Positive
バイアスリスク: Unclear

Abstract

Aged people are the most susceptible group to COVID-19 infection. Immunosenescence characterized by impairment of immune function with inflamm-aging contributes to pathophysiological alterations, among which endocrine and metabolic diseases are not exception. Diabetes, obesity along with impairment of disorders of thyroid functions are the most frequent ones, the common feature of which is failure of immune system including autoimmune processes. In the minireview we discussed how COVID-19 and aging impact innate and adaptive immunity, diabetes and selected neuroendocrine processes. Mentioned is also beneficial effect of vitamin D for attenuation of these diseases and related epigenetic issues. Particular attention is devoted to the role of ACE2 protein in the light of its intimate link with renin-angiotensin regulating system.

要約

In the minireview, it is discussed how COVID-19 and aging impact innate and adaptive immunity, diabetes and selected neuroendocrine processes, and beneficial effect of vitamin D for attenuation of these diseases and related epigenetic issues.

Used In Evidence Reviews

B Vitamin D ： Immune Aging (Immunosenescence)

Endocrine risk factors for COVID-19 in context of aging.

Embed This Widget

Study Design

Abstract

要約

Used In Evidence Reviews

Similar Papers

Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey.

Systemic lupus erythematosus: Diagnosis and clinical management.

Vitamin D and the immune system.

Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections.

Primary prevention of colorectal cancer.

Osteosarcopenia: epidemiology, diagnosis, and treatment-facts and numbers.