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Glutamine para Exercise-Induced Immune Suppression

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Glutamine is part of clinical immunonutrition protocols. Depletion during intense exercise is associated with increased infection risk. Supplementation may help support gut barrier integrity and immune cell metabolism during heavy training periods.

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Conclusão

Glutamine is part of clinical immunonutrition protocols. Depletion during intense exercise is associated with increased infection risk. Supplementation may help support gut barrier integrity and immune cell metabolism during heavy training periods.

Key Study Findings

Review
Performance and altitude: Ways that nutrition can help.
Dose: None vs: None Outcome: None Efeito: None None

População: None

Review
Importance of exercise immunology in health promotion.
Dose: None vs: None Outcome: immune function Efeito: None None

População: heart failure patients

Randomized Controlled Trial 104.0 weeks
Selenium and glutamine supplements: where are we heading? A critical care perspective.
Dose: None vs: None Outcome: mortality Efeito: None None

População: None

Review
Exercise immunology: nutritional countermeasures.
Dose: Vitamin C, E, glutamine, zinc vs: None Outcome: Immune function during exercise Efeito: None None

População: Athletes

Review
Exercise immunology: future directions for research related to athletes, nutrition, and the elderly.
Dose: None vs: placebo Outcome: body weight Efeito: None None

População: athletes

Observational Study 2.0 weeks
Is infection risk linked to exercise workload?
Dose: None vs: None Outcome: immune function Efeito: None None

População: athletes

Key Statistics

10

Estudos

800

Participantes

Positive

B

Nota

Referenced Papers

Nutrition (Burbank, Los … 2019 11 citações
Amino acids 2011 45 citações
Canadian journal of … 2001 72 citações
Medicine and science … 2000 262 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:
5-10 g/day
immunesupport:
10-20 g/day during illness or stress

Limite superior: 40 g/day (supplemental)

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
None -- Mixed --
None -- Mixed --
None 104.0 weeks Positive --
Vitamin C, E, glutamine, zinc -- Positive --
None -- Mixed --
None 2.0 weeks Mixed --

Melhor horário: Between meals or post-exercise; can be divided into multiple doses

Safety & Side Effects

Efeitos Colaterais Relatados

  • Generally well tolerated
  • Bloating and gastrointestinal discomfort at high doses
  • Headache (rare)
  • Contraindicated in hepatic encephalopathy

Interações Conhecidas

  • Lactulose (glutamine may reduce lactulose effectiveness)
  • Anti-seizure medications (may alter seizure threshold)
  • Chemotherapy agents (consult oncologist before use)

Ingestão máxima tolerável: 40 g/day (supplemental)

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Glutamine help with Exercise-Induced Immune Suppression?
Based on 10 studies with 800 participants, there is moderate evidence from clinical studies that Glutamine may support Exercise-Induced Immune Suppression management. Our evidence grade is B (Good Evidence).
How much Glutamine should I take for Exercise-Induced Immune Suppression?
Studies have used various dosages. A commonly studied range is 5-10 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Glutamine?
Reported side effects may include Generally well tolerated, Bloating and gastrointestinal discomfort at high doses, Headache (rare), Contraindicated in hepatic encephalopathy. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Glutamine and Exercise-Induced Immune Suppression?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.

Related Evidence

Outros ingredientes para Exercise-Induced Immune Suppression

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.