Glutamine 用于 运动诱导免疫抑制
B 证据 至少一项随机试验支持这一结论,结果基本一致。Glutamine is part of clinical immunonutrition protocols. Depletion during intense exercise is associated with increased infection risk. Supplementation may help support gut barrier integrity and immune cell metabolism during heavy training periods.
结论
Glutamine is part of clinical immunonutrition protocols. Depletion during intense exercise is associated with increased infection risk. Supplementation may help support gut barrier integrity and immune cell metabolism during heavy training periods.
Key Study Findings
研究人群: None
研究人群: heart failure patients
研究人群: None
研究人群: Athletes
研究人群: athletes
研究人群: athletes
Key Statistics
10
研究数量
800
受试者
Positive
等级
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 5-10 g/day
- immunesupport:
- 10-20 g/day during illness or stress
上限: 40 g/day (supplemental)
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | 104.0 weeks | Positive | -- |
| Vitamin C, E, glutamine, zinc | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | 2.0 weeks | Mixed | -- |
最佳服用时间: Between meals or post-exercise; can be divided into multiple doses
Safety & Side Effects
已报告的副作用
- ⚠ Generally well tolerated
- ⚠ Bloating and gastrointestinal discomfort at high doses
- ⚠ Headache (rare)
- ⚠ Contraindicated in hepatic encephalopathy
已知相互作用
- ● Lactulose (glutamine may reduce lactulose effectiveness)
- ● Anti-seizure medications (may alter seizure threshold)
- ● Chemotherapy agents (consult oncologist before use)
可耐受最高摄入量: 40 g/day (supplemental)
在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Glutamine help with 运动诱导免疫抑制?
How much Glutamine should I take for 运动诱导免疫抑制?
Are there side effects of Glutamine?
How strong is the evidence for Glutamine and 运动诱导免疫抑制?
Related Evidence
其他成分用于 运动诱导免疫抑制
References
- [1] Aline V Caris et al.. Nutrition. 2019. Performance and altitude: Ways that nutrition can help. doi:10.1016/j.nut.2018.09.030 PubMed
- [2] J C Rosa Neto et al.. Amino Acids. 2011. Importance of exercise immunology in health promotion. doi:10.1007/s00726-010-0786-x PubMed
- [3] Peter J D Andrews. Curr Opin Clin Nutr Metab Care. 2010. Selenium and glutamine supplements: where are we heading? A critical care perspective. doi:10.1097/MCO.0b013e32833617cd PubMed
- [4] D C Nieman. Can J Appl Physiol. 2001. Exercise immunology: nutritional countermeasures. doi:10.1139/h2001-041 PubMed
- [5] D C Nieman. Med Sci Sports Exerc. 2000. Is infection risk linked to exercise workload? doi:10.1097/00005768-200007001-00005 PubMed
- [6] D C Nieman. Int J Sports Med. 2000. Exercise immunology: future directions for research related to athletes, nutrition, and the elderly. doi:10.1055/s-2000-1453 PubMed
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