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ImmuneCited

Zinc cho Upper Respiratory Tract Infections

A

Meta-analysis of 7 trials demonstrates zinc lozenges at 75+ mg/day may reduce cold duration by 33% when started within 24 hours of symptom onset. Zinc acetate lozenges at 80-92 mg/day showed 40% duration reduction. Doses below 75 mg/day showed no effect.

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Kết luận

Meta-analysis of 7 trials demonstrates zinc lozenges at 75+ mg/day may reduce cold duration by 33% when started within 24 hours of symptom onset. Zinc acetate lozenges at 80-92 mg/day showed 40% duration reduction. Doses below 75 mg/day showed no effect.

Key Study Findings

Observational Study n=107 Open-label
Additive effect of free-choice olfactory training combined with pharmacotherapy: A retrospective analysis of post-viral olfactory …
Dose: tokishakuyakusan, zinc sulfate, methylcobalamin so với: medication alone Outcome: olfactory function improvement via T&T olfactometry Hiệu quả: OR=4.96 p=0.009

Đối tượng nghiên cứu: patients with post-viral olfactory dysfunction (non-COVID)

Review
Exploiting the vulnerability of SARS-CoV-2 with a partnership of mucosal immune function and nutrition: a …
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: None

Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Elite/professional cyclists nutrition review

Meta-Analysis
Effect of Oral Nutritional Supplementation on Health-Related Outcomes and Nutritional Biomarkers in Children and Adolescents …
Dose: Various oral nutritional supplements so với: Standard diet or placebo Outcome: Health outcomes and nutritional biomarkers Hiệu quả: None None

Đối tượng nghiên cứu: Children/adolescents with undernutrition

Controlled Clinical Trial n=120 5 weeks Single-blind
Single-Center-Single-Blinded Clinical Trial to Evaluate the Efficacy of a Nutraceutical Containing Boswellia Serrata, Bromelain, Zinc, …
Dose: 20 or 30 days treatment so với: Standard treatment only (nasal aerosol) Outcome: Otoscopy, impedance, fibroscopy, pure auditory test Hiệu quả: None None

Đối tượng nghiên cứu: Children with otitis media

Review
Associations of fine particulate matter and constituents with pediatric emergency room visits for respiratory diseases …
Dose: 31 μg so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: respiratory disease

Key Statistics

15

Nghiên cứu

1500

Người tham gia

Positive

A

Xếp hạng

Referenced Papers

Advances in nutrition … 2013 807 trích dẫn
Pakistan journal of … 2013 33 trích dẫn
Acta scientiarum polonorum. … 2012 11 trích dẫn
American family physician 2012
International journal of … 2011 49 trích dẫn
Nihon Jibiinkoka Gakkai … 2009 1 trích dẫn
The Cochrane database … 2007 24 trích dẫn
Clinical evidence 2003
Clinical evidence 2003
American family physician 2002
Canadian journal of … 2001 72 trích dẫn
Zinc for the common cold. Systematic Review
The Cochrane database … 2000 294 trích dẫn
European journal of … 1996 54 trích dẫn
Nederlands tijdschrift voor … 1991
Clinica chimica acta; … 1986 15 trích dẫn
Southern medical journal 1978 3 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:
8-11 mg/day
coldtreatment:
75-100 mg/day elemental zinc (lozenges, within 24h of onset, up to 2 weeks)
immunesupport:
15-30 mg/day

Giới hạn trên: 40 mg/day (long-term)

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
tokishakuyakusan, zinc sulfate, methylcobalamin -- Positive 107
None -- Mixed --
None -- Mixed --
Various oral nutritional supplements -- Positive --
20 or 30 days treatment 5 weeks Positive 120
31 μg -- Neutral --
94.57% -- Mixed --
None -- Mixed 387

Thời điểm dùng tốt nhất: Lozenges: dissolve slowly in mouth every 2-3h at cold onset; Supplements: with food to minimize nausea

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • Nausea and vomiting (especially on an empty stomach)
  • Metallic taste in the mouth
  • Copper depletion with chronic high-dose use (>40 mg/day)
  • Headache and diarrhea

Tương tác đã biết

  • Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)
  • Iron supplements (mutual absorption interference when taken together)

Mức hấp thụ tối đa cho phép: 40 mg/day (long-term)

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Zinc help with Upper Respiratory Tract Infections?
Based on 15 studies with 1,500 participants, there is strong evidence from multiple clinical trials that Zinc may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).
How much Zinc should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zinc?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use (>40 mg/day), Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zinc and Upper Respiratory Tract Infections?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.

Related Evidence

Các thành phần khác cho Upper Respiratory Tract Infections

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.