Astaxanthin 用于 Oxidative Stress
CSmall randomized trials show astaxanthin supplementation may enhance IgM and IgG immunoglobulin production and T-cell function. Evidence is early-stage but consistent across multiple small trials, with astaxanthin's potent antioxidant capacity well-established.
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'immunecited.com';
const params = 'ingredient\u003Dastaxanthin\u0026condition\u003Doxidative\u002Dstress';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
C
结论
Small randomized trials show astaxanthin supplementation may enhance IgM and IgG immunoglobulin production and T-cell function. Evidence is early-stage but consistent across multiple small trials, with astaxanthin's potent antioxidant capacity well-established.
Key Study Findings
Review
Carotenoids for Antiaging: Nutraceutical, Pharmaceutical, and Cosmeceutical Applications.
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: systematic review of carotenoids for antiaging (nutraceutical, pharmaceutical, cosmeceutical)
In Vitro
Astaxanthin Alleviates Oxidative Stress in Mouse Preantral Follicles and Enhances Follicular Development Through the AMPK …
Dose: 2.5 nM
vs: Control follicle culture
Outcome: Follicular development and oxidative stress
效果: Antrum formation 85.96% to 94.38%
p<0.05
研究人群: Mouse preantral follicles in vitro culture
In Vitro
Astaxanthin Mitigates 5-Fluorouracil-Induced Hepatotoxicity and Oxidative Stress in Male Rats.
Dose: 16 and 32 mg/kg/bw
vs: 5-FU induced liver damage in rats
Outcome: Hepatotoxicity and oxidative stress markers
效果: None
p<0.001
研究人群: Rats with 5-FU-induced liver damage
Other
Astaxanthin Promotes Spermatogenesis in Mice by Reducing Mitochondrial Oxidative Stress Damage and Regulating Fatty Acid …
Dose: None
vs: Quercetin group; oligoasthenozoospermia control mice
Outcome: Sperm concentration and forward motility
效果: None
None
研究人群: Cyclophosphamide-induced oligoasthenozoospermia mice
In Vitro
Mechanism Exploration of Dietary Supplement Astaxanthin on Improving Atherosclerosis through an Integrated Strategy Encompassing Artificial …
Dose: None
vs: None
Outcome: Inhibition of foam cell formation and inflammation
效果: None
None
研究人群: In vitro atherosclerosis cell model
Other
1 weeks
Astaxanthin ameliorates benzalkonium chloride-induced dry eye disease through suppressing inflammation and oxidative stress via Keap1-Nrf2/HO-1 …
Dose: 100 mg/kg/day
vs: Untreated BAC-induced DED mice
Outcome: Dry eye disease severity and oxidative stress
效果: None
None
研究人群: BAC-induced dry eye disease mouse model + hCEC cells
Key Statistics
3
研究数量
100
受试者
↑
Positive
C
等级
Referenced Papers
Pharmaceuticals (Basel, Switzerland)
2025
28 次引用
International journal of …
2025
7 次引用
Astaxanthin Mitigates 5-Fluorouracil-Induced Hepatotoxicity and Oxidative Stress in Male Rats.
Other
Nutrients
2025
7 次引用
Journal of agricultural …
2025
6 次引用
Redox biology
2025
6 次引用
Animal models and …
2025
6 次引用
ACS nano
2025
6 次引用
Naunyn-Schmiedeberg's archives of …
2025
3 次引用
Scientific reports
2025
3 次引用
Biology
2025
3 次引用
Drug design, development …
2025
2 次引用
Molecules (Basel, Switzerland)
2025
Scientific reports
2025
Ecotoxicology and environmental …
2024
38 次引用
Phytotherapy research : …
2024
24 次引用
Advanced healthcare materials
2024
14 次引用
Biomedicine & pharmacotherapy …
2024
13 次引用
Biochemical Society transactions
2024
13 次引用
The Effects of Astaxanthin on Cognitive Function and Neurodegeneration in Humans: A Critical Review.
Review
Nutrients
2024
10 次引用
Journal of the …
2024
10 次引用
Nutrients
2024
9 次引用
Journal of ovarian …
2024
9 次引用
Journal of ovarian …
2024
8 次引用
Nutrients
2024
5 次引用
Cell biochemistry and …
2024
3 次引用
Critical reviews in …
2023
105 次引用
Frontiers in endocrinology
2023
44 次引用
International immunopharmacology
2023
40 次引用
Biomedicine & pharmacotherapy …
2023
30 次引用
Toxins
2023
26 次引用
Acta histochemica
2023
24 次引用
Antioxidants (Basel, Switzerland)
2023
22 次引用
Chemico-biological interactions
2023
19 次引用
Journal of biochemical …
2023
1 次引用
ACS applied materials …
2022
151 次引用
Molecules (Basel, Switzerland)
2022
74 次引用
Open heart
2022
52 次引用
Nutrients
2022
51 次引用
Nutrition research (New …
2022
31 次引用
Neurochemical research
2022
13 次引用
Food & function
2022
10 次引用
Marine drugs
2022
10 次引用
Nutrients
2022
9 次引用
Marine drugs
2021
153 次引用
British journal of …
2021
139 次引用
Oxidative medicine and …
2021
31 次引用
Biogerontology
2021
25 次引用
Redox biology
2020
184 次引用
Marine drugs
2020
59 次引用
Bioresource technology
2020
56 次引用
Pharmacological reports : …
2020
56 次引用
The Journal of …
2020
43 次引用
Journal of toxicology …
2019
33 次引用
Nutrients
2018
253 次引用
Astaxanthin Prevented Oxidative Stress in Heart and Kidneys of Isoproterenol-Administered Aged Rats.
Other
Journal of dietary …
2018
64 次引用
Frontiers in nutrition
2017
68 次引用
Marine drugs
2016
192 次引用
PloS one
2016
127 次引用
Molecular medicine reports
2016
48 次引用
Behavioural brain research
2015
118 次引用
Postepy higieny i …
2015
72 次引用
Future cardiology
2009
176 次引用
Current atherosclerosis reports
2009
122 次引用
The American journal …
2008
441 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 4-12 mg/day
上限： No established UL; well-tolerated up to 40 mg/day
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| 2.5 nM | -- | Positive | -- |
| 16 and 32 mg/kg/bw | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 100 mg/kg/day | 1 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
最佳服用时间： With meals containing fat
Safety & Side Effects
已报告的副作用
- ⚠ Mild orange skin discoloration at very high doses
- ⚠ Gastrointestinal discomfort
- ⚠ Generally very well tolerated
已知相互作用
- ● Anticoagulants (theoretical interaction due to antioxidant effects)
- ● Blood pressure medications (may have additive effects)
- ● 5-alpha-reductase inhibitors (theoretical hormonal interaction)
可耐受最高摄入量： No established UL; well-tolerated up to 40 mg/day
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Astaxanthin help with Oxidative Stress?
Based on 3 studies with 100 participants, there is limited but promising evidence that Astaxanthin may support Oxidative Stress management. Our evidence grade is C (Some Evidence).
How much Astaxanthin should I take for Oxidative Stress?
Studies have used various dosages. A commonly studied range is 4-12 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Astaxanthin?
Reported side effects may include Mild orange skin discoloration at very high doses, Gastrointestinal discomfort, Generally very well tolerated. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Astaxanthin and Oxidative Stress?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
FDA 免责声明: 这些声明未经美国食品药品监督管理局（FDA）评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析，不构成医疗建议。在开始任何补充剂方案之前，请务必咨询您的医疗保健提供者。