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Astaxanthin für Oxidative Stress

C

Small randomized trials show astaxanthin supplementation may enhance IgM and IgG immunoglobulin production and T-cell function. Evidence is early-stage but consistent across multiple small trials, with astaxanthin's potent antioxidant capacity well-established.

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C

Fazit

Small randomized trials show astaxanthin supplementation may enhance IgM and IgG immunoglobulin production and T-cell function. Evidence is early-stage but consistent across multiple small trials, with astaxanthin's potent antioxidant capacity well-established.

Key Study Findings

Review
Therapeutic Potentials of the Seaweed-Derived Compounds for Alzheimer's Disease.
Dose: None vs.: None Outcome: None Wirkung: None None

Population: None

Randomized Controlled Trial n=90 8 weeks
Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and …
Dose: 8 mg/day astaxanthin vs.: Control, placebo, AST alone, CT alone, CT+placebo Outcome: Oxidative stress and inflammatory markers in T2DM Wirkung: None <0.05

Population: 90 women with type 2 diabetes mellitus (6 groups, n=15)

Review
Carotenoids for Antiaging: Nutraceutical, Pharmaceutical, and Cosmeceutical Applications.
Dose: None vs.: None Outcome: None Wirkung: None None

Population: systematic review of carotenoids for antiaging (nutraceutical, pharmaceutical, cosmeceutical)

In Vitro
Astaxanthin Alleviates Oxidative Stress in Mouse Preantral Follicles and Enhances Follicular Development Through the AMPK …
Dose: 2.5 nM vs.: Control follicle culture Outcome: Follicular development and oxidative stress Wirkung: Antrum formation 85.96% to 94.38% p<0.05

Population: Mouse preantral follicles in vitro culture

In Vitro
Astaxanthin Mitigates 5-Fluorouracil-Induced Hepatotoxicity and Oxidative Stress in Male Rats.
Dose: 16 and 32 mg/kg/bw vs.: 5-FU induced liver damage in rats Outcome: Hepatotoxicity and oxidative stress markers Wirkung: None p<0.001

Population: Rats with 5-FU-induced liver damage

Other
Astaxanthin Promotes Spermatogenesis in Mice by Reducing Mitochondrial Oxidative Stress Damage and Regulating Fatty Acid …
Dose: None vs.: Quercetin group; oligoasthenozoospermia control mice Outcome: Sperm concentration and forward motility Wirkung: None None

Population: Cyclophosphamide-induced oligoasthenozoospermia mice

Key Statistics

3

Studien

100

Teilnehmer

Positive

C

Bewertung

Referenced Papers

Pharmaceuticals (Basel, Switzerland) 2025 28 Zitierungen
Biochemical Society transactions 2024 13 Zitierungen
Critical reviews in … 2023 105 Zitierungen
Antioxidants (Basel, Switzerland) 2023 22 Zitierungen
Molecules (Basel, Switzerland) 2022 74 Zitierungen
Open heart 2022 52 Zitierungen
Frontiers in nutrition 2017 68 Zitierungen
Marine drugs 2016 192 Zitierungen
Postepy higieny i … 2015 72 Zitierungen
Current atherosclerosis reports 2009 122 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
4-12 mg/day

Obergrenze: No established UL; well-tolerated up to 40 mg/day

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None -- Mixed --
8 mg/day astaxanthin 8 weeks Positive 90
None -- Positive --
2.5 nM -- Positive --
16 and 32 mg/kg/bw -- Positive --
None -- Positive --
None -- Positive --
100 mg/kg/day 1 weeks Positive --

Beste Einnahmezeit: With meals containing fat

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Mild orange skin discoloration at very high doses
  • Gastrointestinal discomfort
  • Generally very well tolerated

Bekannte Wechselwirkungen

  • Anticoagulants (theoretical interaction due to antioxidant effects)
  • Blood pressure medications (may have additive effects)
  • 5-alpha-reductase inhibitors (theoretical hormonal interaction)

Tolerierbare Höchstaufnahmemenge: No established UL; well-tolerated up to 40 mg/day

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Astaxanthin help with Oxidative Stress?
Based on 3 studies with 100 participants, there is limited but promising evidence that Astaxanthin may support Oxidative Stress management. Our evidence grade is C (Some Evidence).
How much Astaxanthin should I take for Oxidative Stress?
Studies have used various dosages. A commonly studied range is 4-12 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Astaxanthin?
Reported side effects may include Mild orange skin discoloration at very high doses, Gastrointestinal discomfort, Generally very well tolerated. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Astaxanthin and Oxidative Stress?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

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