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ImmuneCited

Astaxanthin لـ Oxidative Stress

C

Small randomized trials show astaxanthin supplementation may enhance IgM and IgG immunoglobulin production and T-cell function. Evidence is early-stage but consistent across multiple small trials, with astaxanthin's potent antioxidant capacity well-established.

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الخلاصة

Small randomized trials show astaxanthin supplementation may enhance IgM and IgG immunoglobulin production and T-cell function. Evidence is early-stage but consistent across multiple small trials, with astaxanthin's potent antioxidant capacity well-established.

Key Study Findings

Review
Therapeutic Potentials of the Seaweed-Derived Compounds for Alzheimer's Disease.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: None

Randomized Controlled Trial n=90 8 weeks
Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and …
Dose: 8 mg/day astaxanthin مقابل: Control, placebo, AST alone, CT alone, CT+placebo Outcome: Oxidative stress and inflammatory markers in T2DM التأثير: None <0.05

المجتمع المدروس: 90 women with type 2 diabetes mellitus (6 groups, n=15)

Review
Carotenoids for Antiaging: Nutraceutical, Pharmaceutical, and Cosmeceutical Applications.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: systematic review of carotenoids for antiaging (nutraceutical, pharmaceutical, cosmeceutical)

In Vitro
Astaxanthin Alleviates Oxidative Stress in Mouse Preantral Follicles and Enhances Follicular Development Through the AMPK …
Dose: 2.5 nM مقابل: Control follicle culture Outcome: Follicular development and oxidative stress التأثير: Antrum formation 85.96% to 94.38% p<0.05

المجتمع المدروس: Mouse preantral follicles in vitro culture

In Vitro
Astaxanthin Mitigates 5-Fluorouracil-Induced Hepatotoxicity and Oxidative Stress in Male Rats.
Dose: 16 and 32 mg/kg/bw مقابل: 5-FU induced liver damage in rats Outcome: Hepatotoxicity and oxidative stress markers التأثير: None p<0.001

المجتمع المدروس: Rats with 5-FU-induced liver damage

Other
Astaxanthin Promotes Spermatogenesis in Mice by Reducing Mitochondrial Oxidative Stress Damage and Regulating Fatty Acid …
Dose: None مقابل: Quercetin group; oligoasthenozoospermia control mice Outcome: Sperm concentration and forward motility التأثير: None None

المجتمع المدروس: Cyclophosphamide-induced oligoasthenozoospermia mice

Key Statistics

3

الدراسات

100

المشاركون

Positive

C

التقييم

Referenced Papers

Pharmaceuticals (Basel, Switzerland) 2025 28 اقتباسات
Biochemical Society transactions 2024 13 اقتباسات
Critical reviews in … 2023 105 اقتباسات
Antioxidants (Basel, Switzerland) 2023 22 اقتباسات
Molecules (Basel, Switzerland) 2022 74 اقتباسات
Open heart 2022 52 اقتباسات
Frontiers in nutrition 2017 68 اقتباسات
Marine drugs 2016 192 اقتباسات
Postepy higieny i … 2015 72 اقتباسات
Future cardiology 2009 176 اقتباسات
Current atherosclerosis reports 2009 122 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
4-12 mg/day

الحد الأعلى: No established UL; well-tolerated up to 40 mg/day

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
None -- Mixed --
8 mg/day astaxanthin 8 weeks Positive 90
None -- Positive --
2.5 nM -- Positive --
16 and 32 mg/kg/bw -- Positive --
None -- Positive --
None -- Positive --
100 mg/kg/day 1 weeks Positive --

أفضل وقت للتناول: With meals containing fat

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Mild orange skin discoloration at very high doses
  • Gastrointestinal discomfort
  • Generally very well tolerated

التفاعلات المعروفة

  • Anticoagulants (theoretical interaction due to antioxidant effects)
  • Blood pressure medications (may have additive effects)
  • 5-alpha-reductase inhibitors (theoretical hormonal interaction)

الحد الأقصى المسموح به: No established UL; well-tolerated up to 40 mg/day

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Astaxanthin help with Oxidative Stress?
Based on 3 studies with 100 participants, there is limited but promising evidence that Astaxanthin may support Oxidative Stress management. Our evidence grade is C (Some Evidence).
How much Astaxanthin should I take for Oxidative Stress?
Studies have used various dosages. A commonly studied range is 4-12 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Astaxanthin?
Reported side effects may include Mild orange skin discoloration at very high doses, Gastrointestinal discomfort, Generally very well tolerated. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Astaxanthin and Oxidative Stress?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.