Glutamine 用于 Exercise-Induced Immune Suppression

Glutamine is part of clinical immunonutrition protocols. Depletion during intense exercise is associated with increased infection risk. Supplementation may help support gut barrier integrity and immune cell metabolism during heavy training periods.

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结论

Key Study Findings

Review

Performance and altitude: Ways that nutrition can help.

Dose: None vs: None Outcome: None 效果: None None

研究人群: None

Review

Importance of exercise immunology in health promotion.

Dose: None vs: None Outcome: immune function 效果: None None

研究人群: heart failure patients

Randomized Controlled Trial 104.0 weeks

Selenium and glutamine supplements: where are we heading? A critical care perspective.

Dose: None vs: None Outcome: mortality 效果: None None

研究人群: None

Review

Exercise immunology: nutritional countermeasures.

Dose: Vitamin C, E, glutamine, zinc vs: None Outcome: Immune function during exercise 效果: None None

研究人群: Athletes

Review

Exercise immunology: future directions for research related to athletes, nutrition, and the elderly.

Dose: None vs: placebo Outcome: body weight 效果: None None

研究人群: athletes

Observational Study 2.0 weeks

Is infection risk linked to exercise workload?

Dose: None vs: None Outcome: immune function 效果: None None

研究人群: athletes

Key Statistics

研究数量

800

受试者

↑

Positive

等级

Referenced Papers

Performance and altitude: Ways that nutrition can help. Review

Nutrition (Burbank, Los … 2019 11 次引用

Importance of exercise immunology in health promotion. Review

Amino acids 2011 45 次引用

Selenium and glutamine supplements: where are we heading? A critical care perspective. Review

Current opinion in … 2010 18 次引用

Exercise immunology: nutritional countermeasures. Review

Canadian journal of … 2001 72 次引用

Is infection risk linked to exercise workload? Review

Medicine and science … 2000 262 次引用

Exercise immunology: future directions for research related to athletes, nutrition, and the elderly. Review

International journal of … 2000 57 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 5-10 g/day
immunesupport:: 10-20 g/day during illness or stress

上限： 40 g/day (supplemental)

研究中使用的剂量

剂量	持续时间	效果	N
None	--	Mixed	--
None	--	Mixed	--
None	104.0 weeks	Positive	--
Vitamin C, E, glutamine, zinc	--	Positive	--
None	--	Mixed	--
None	2.0 weeks	Mixed	--

最佳服用时间： Between meals or post-exercise; can be divided into multiple doses

Safety & Side Effects

已报告的副作用

⚠ Generally well tolerated
⚠ Bloating and gastrointestinal discomfort at high doses
⚠ Headache (rare)
⚠ Contraindicated in hepatic encephalopathy

已知相互作用

● Lactulose (glutamine may reduce lactulose effectiveness)
● Anti-seizure medications (may alter seizure threshold)
● Chemotherapy agents (consult oncologist before use)

可耐受最高摄入量： 40 g/day (supplemental)

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Glutamine help with Exercise-Induced Immune Suppression?

Based on 10 studies with 800 participants, there is moderate evidence from clinical studies that Glutamine may support Exercise-Induced Immune Suppression management. Our evidence grade is B (Good Evidence).

How much Glutamine should I take for Exercise-Induced Immune Suppression?

Studies have used various dosages. A commonly studied range is 5-10 g/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Glutamine?

Reported side effects may include Generally well tolerated, Bloating and gastrointestinal discomfort at high doses, Headache (rare), Contraindicated in hepatic encephalopathy. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Glutamine and Exercise-Induced Immune Suppression?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.

Related Evidence

其他成分用于 Exercise-Induced Immune Suppression

Vitamin C B

快速结论

Evidence Strength72%

High confidence

研究分析

RCT (0)Meta (0)Other (10)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于 Exercise-Induced Immune Suppression

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