Omega-3 Fatty Acids (EPA/DHA)Omega-3 Fatty Acids (EPA/DHA)
fatty_acid
别名: Fish Oil, Eicosapentaenoic Acid, Docosahexaenoic Acid, Marine Omega-3
About
EPA and DHA alter cell membrane phospholipid composition and give rise to specialized pro-resolving mediators (resolvins, protectins, maresins) that actively resolve inflammation. The VITAL trial showed a 15% reduction in autoimmune disease risk. DHA showed stronger anti-inflammatory effects than EPA in randomized studies.
How It Works
EPA and DHA alter cell membrane phospholipid composition and give rise to specialized pro-resolving mediators (resolvins, protectins, maresins); EPA inhibits NF-kB activation; DHA suppresses pro-inflammatory gene expression.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| Chronic Inflammation | A | 30 | 30000 | 查看 → |
| Autoimmune Conditions | B | 10 | 25000 | 查看 → |
Side Effects
- Fishy aftertaste and burping
- Gastrointestinal discomfort (nausea, diarrhea)
- Increased bleeding risk at high doses
- Potential LDL cholesterol increase at very high doses
Drug & Supplement Interactions
- Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- Blood pressure medications (additive blood pressure lowering)
- Orlistat (may reduce omega-3 absorption)
- Cyclosporine (may modify immunosuppressive effects)
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Related Ingredients
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