Skip to main content
ImmuneCited

Conjugated Linoleic Acid لـ Chronic Inflammation

D

Animal studies show CLA may have immunomodulatory effects via PPAR-gamma activation. Human evidence for immune-specific outcomes is limited and inconsistent, with some studies showing no significant benefit.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'immunecited.com'; const params = 'ingredient\u003Dcla\u0026condition\u003Dchronic\u002Dinflammation'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    

Widget powered by . Free, no account required.

D

الخلاصة

Animal studies show CLA may have immunomodulatory effects via PPAR-gamma activation. Human evidence for immune-specific outcomes is limited and inconsistent, with some studies showing no significant benefit.

Key Study Findings

Review
A perspective on the chemical structures and molecular mechanisms of curcumin and its derivatives and …
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: Review of curcumin derivatives in cancer treatment

Review
Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: review of dietary polyphenols in type 2 diabetes mellitus management

Review
Which Approach to Choose to Counteract Musculoskeletal Aging? A Comprehensive Review on the Multiple Effects …
Dose: None مقابل: None Outcome: Musculoskeletal aging and cellular senescence التأثير: None None

المجتمع المدروس: Aging adults with musculoskeletal decline (review)

Review
Retracted: Chronic Epipharyngitis Treated with Epipharyngeal Abrasion Therapy: Symptoms, Diagnosis, Pathogenesis, and Treatment Outcomes.
Dose: 1% zinc chloride solution مقابل: None Outcome: Chronic epipharyngitis symptom improvement التأثير: None None

المجتمع المدروس: Patients with chronic epipharyngitis (retracted publication)

Systematic Review
Research progress on traditional Chinese medicine compounds in autoimmune-related skin diseases.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: Review of TCM compounds in autoimmune skin diseases

Other
The omega effect: Harnessing fish oil for health.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: None

Key Statistics

3

الدراسات

150

المشاركون

Mixed

D

التقييم

Referenced Papers

Frontiers in immunology 2025 1 اقتباسات
Newborn (Clarksville, Md.) 2024 9 اقتباسات
International immunopharmacology 2023 8 اقتباسات
Current pharmaceutical design 2017 168 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
1.5-3 g/day

الحد الأعلى: No established UL

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
None -- Mixed --
None -- Positive --
None -- Positive --
1% zinc chloride solution -- Positive --
None -- Mixed --
None -- Mixed --
200 mg 5 weeks Positive --
None -- Positive --

أفضل وقت للتناول: With meals

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Gastrointestinal discomfort (nausea, diarrhea)
  • Fatigue
  • May worsen insulin sensitivity in some individuals
  • Liver fat accumulation (some formulations)

التفاعلات المعروفة

  • Diabetes medications (may affect insulin sensitivity)
  • Anticoagulants (may have additive effects)

الحد الأقصى المسموح به: No established UL

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Conjugated Linoleic Acid help with Chronic Inflammation?
Based on 3 studies with 150 participants, there is preliminary evidence that needs more research that Conjugated Linoleic Acid may support Chronic Inflammation management. Our evidence grade is D (Very Early Research).
How much Conjugated Linoleic Acid should I take for Chronic Inflammation?
Studies have used various dosages. A commonly studied range is 1.5-3 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Conjugated Linoleic Acid?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea), Fatigue, May worsen insulin sensitivity in some individuals, Liver fat accumulation (some formulations). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Conjugated Linoleic Acid and Chronic Inflammation?
We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is mixed.

Related Evidence

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.