Beta-Glucan ： Upper Respiratory Tract Infections

Q: Does Beta-Glucan help with Upper Respiratory Tract Infections?

Based on 13 studies with 2,000 participants, there is strong evidence from multiple clinical trials that Beta-Glucan may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).

Q: How much Beta-Glucan should I take for Upper Respiratory Tract Infections?

Studies have used various dosages. A commonly studied range is 250-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Beta-Glucan?

Reported side effects may include Generally very well tolerated, Mild gastrointestinal effects (bloating), Allergic reactions in yeast-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Beta-Glucan and Upper Respiratory Tract Infections?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 13 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.

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結論

Key Study Findings

Randomized Controlled Trial

The anti-infective effect of β-glucans in children.

Dose: 10 mg vs: Placebo Outcome: Body weight 効果: None None

対象集団: None

In Vitro

Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's …

Dose: 250 mg/d vs: None Outcome: oxidative stress markers 効果: None None

対象集団: None

Randomized Controlled Trial 12 weeks Double-blind

β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and …

Dose: None vs: Placebo Outcome: Protective Qi status improvement 効果: None None

対象集団: Adults with Protective Qi deficiency

Meta-Analysis

Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in …

Dose: 95% vs: placebo Outcome: None 効果: OR = 0.345 p < 0.001

対象集団: healthy subjects

Randomized Controlled Trial n=69

Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A …

Dose: 250 mL/d vs: Placebo Outcome: None 効果: None None

対象集団: URTI patients

Randomized Controlled Trial n=132 Double-blind

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled …

Dose: 250 mL/d vs: Placebo Outcome: None 効果: None p < .05

対象集団: URTI patients

Key Statistics

研究数

2000

参加者数

↑

Positive

グレード

Referenced Papers

The anti-infective effect of β-glucans in children. Review

International journal for … 2024 5 件の引用

Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's yeast beta glucan. Other

Methods (San Diego, … 2023 6 件の引用

β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and Double-Blinded Trial. RCT

Chinese journal of … 2022 2 件の引用

Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review … Meta-Analysis

European journal of … 2021 21 件の引用

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial. RCT

Journal of dietary … 2020 27 件の引用

Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A Double-Blind, Randomized Placebo-Controlled Trial. RCT

Journal of medicinal … 2020 24 件の引用

Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects. RCT

Journal of the … 2019 47 件の引用

Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. RCT

Nutrients 2019 34 件の引用

Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. RCT

Journal of dietary … 2013 99 件の引用

Benefits of oat beta-glucan and sucrose feedings on infection and macrophage antiviral resistance following exercise stress. Other

American journal of … 2009 34 件の引用

Effect of BETA 1, 3/1, 6 GLUCAN on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes. Other

Journal of sports … 2009

Beta-glucan, immune function, and upper respiratory tract infections in athletes. RCT

Medicine and science … 2008 71 件の引用

Benefits of oat beta-glucan on respiratory infection following exercise stress: role of lung macrophages. Other

American journal of … 2008 45 件の引用

Nutritional strategies to counter stress to the immune system in athletes, with special reference to football. Review

Journal of sports … 2006 94 件の引用

Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection. Other

American journal of … 2004 107 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:: 250-500 mg/day
immunesupport:: 250-750 mg/day

上限量： No established UL

研究で検討された用量

用量	期間	効果	N
10 mg	--	Positive	--
250 mg/d	--	Positive	--
None	12 weeks	Positive	--
95%	--	Positive	--
250 mL/d	--	Mixed	69
250 mL/d	--	Neutral	132
900 mg	16.0 weeks	Positive	299
367 mg	12.9 weeks	Positive	34

推奨摂取タイミング： On empty stomach for optimal immune activation

Safety & Side Effects

報告されている副作用

⚠ Generally very well tolerated
⚠ Mild gastrointestinal effects (bloating)
⚠ Allergic reactions in yeast-sensitive individuals

既知の相互作用

● Immunosuppressant medications (may counteract immunosuppression)
● Generally few known drug interactions

耐容上限摂取量： No established UL

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does Beta-Glucan help with Upper Respiratory Tract Infections?

Based on 13 studies with 2,000 participants, there is strong evidence from multiple clinical trials that Beta-Glucan may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).

How much Beta-Glucan should I take for Upper Respiratory Tract Infections?

Studies have used various dosages. A commonly studied range is 250-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Beta-Glucan?

Reported side effects may include Generally very well tolerated, Mild gastrointestinal effects (bloating), Allergic reactions in yeast-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Beta-Glucan and Upper Respiratory Tract Infections?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 13 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Related Evidence

に関する他の成分： Upper Respiratory Tract Infections

Vitamin D A Zinc A Vitamin C B Echinacea B Andrographis B Garlic B

総合評価

Evidence Strength92%

High confidence

研究の内訳

RCT (7)Meta (1)Other (5)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る： Upper Respiratory Tract Infections

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FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。