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ImmuneCited

Selenium Vaccine Response Support

C

Adequate selenium status is associated with enhanced natural killer cell activity and improved vaccine response, particularly in elderly populations. Supplementation in deficient individuals may help restore optimal immune responses to vaccination.

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結論

Adequate selenium status is associated with enhanced natural killer cell activity and improved vaccine response, particularly in elderly populations. Supplementation in deficient individuals may help restore optimal immune responses to vaccination.

Key Study Findings

Systematic Review and Meta-Analysis n=7014
Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.
Dose: None vs: Placebo 効果: Standardized mean differences reported for each element and disease combination (specific values not None
Review
A scoping review: the impact of nutritional status on the efficacy, effectiveness, and immunogenicity of …
Dose: None vs: None Outcome: None 効果: None None

対象集団: Scoping review: nutritional status and COVID-19 vaccine

Review
Potential Applications and Risks of Supranutritional Selenium Supplementation in Metabolic Dysfunction-Associated Steatotic Liver Disease: A …
Dose: None vs: None Outcome: MASLD treatment and prevention 効果: None None

対象集団: Patients with metabolic steatotic liver disease (review)

Observational Study n=44
Unveiling the micronutrient-immunity puzzle in inactivated COVID-19 vaccination: A comprehensive analysis of circulating micronutrient levels …
Dose: Fe, Zn, Cu, Se, vitamins A, D, E (measured) vs: Pre-vaccination vs post-booster Outcome: Antibody response association with micronutrients 効果: None None

対象集団: Healthy adults post-COVID-19 vaccination

Other
Novel selenium-enriched Pichia kudriavzevii as a dietary supplement to alleviate dextran sulfate sodium-induced colitis in …
Dose: None vs: None Outcome: Colitis severity 効果: None None

対象集団: Mouse model

Other
Effect of parenteral micronutrient supplementation at birth on immunity, growth, and health in preweaning dairy …
Dose: 4 g vs: None Outcome: Oxidative stress markers 効果: None None

対象集団: None

Key Statistics

5

研究数

400

参加者数

Positive

C

グレード

Referenced Papers

The Proceedings of … 2023 27 件の引用
European thyroid journal 2023 4 件の引用
Biological trace element … 2015 1 件の引用
Annual review of … 2014 9 件の引用
European journal of … 2012 225 件の引用
Minerva urologica e … 2012
Archives of internal … 2007 8 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:
55 mcg/day
immunesupport:
100-200 mcg/day

上限量: 400 mcg/day

研究で検討された用量

用量 期間 効果 N
None -- Mixed 7014
None -- Mixed --
None -- Mixed --
Fe, Zn, Cu, Se, vitamins A, D, E (measured) -- Positive 44
None -- Positive --
4 g -- Positive --
Selenium supplement (dose not specified) -- Neutral 105
Various inorganic and organic selenium forms; dose-response assessed via plasma selenium concentrati -- Mixed --

推奨摂取タイミング: With meals

Safety & Side Effects

報告されている副作用

  • Selenosis at chronic high doses (hair loss, nail brittleness, garlic breath odor)
  • Nausea and diarrhea
  • Fatigue and irritability
  • Nerve damage (peripheral neuropathy) at very high chronic doses

既知の相互作用

  • Cisplatin and other chemotherapy agents (selenium may modify effects)
  • Statins (selenium may affect cholesterol metabolism)
  • Birth control pills (may lower selenium levels)
  • Gold salts (mutual reduction of effectiveness)

耐容上限摂取量: 400 mcg/day

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does Selenium help with Vaccine Response Support?
Based on 5 studies with 400 participants, there is limited but promising evidence that Selenium may support Vaccine Response Support management. Our evidence grade is C (Some Evidence).
How much Selenium should I take for Vaccine Response Support?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Selenium?
Reported side effects may include Selenosis at chronic high doses (hair loss, nail brittleness, garlic breath odor), Nausea and diarrhea, Fatigue and irritability, Nerve damage (peripheral neuropathy) at very high chronic doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Selenium and Vaccine Response Support?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

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