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ImmuneCited

Garlic 用于 Upper Respiratory Tract Infections

B

A 12-week randomized controlled trial found the garlic group experienced 63% fewer colds, 70% shorter symptom duration, and significantly fewer viral-challenged days (111 vs 365) compared to placebo. While promising, human clinical trials remain limited.

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            B

        

        

            
结论

            
            
A 12-week randomized controlled trial found the garlic group experienced 63% fewer colds, 70% shorter symptom duration, and significantly fewer viral-challenged days (111 vs 365) compared to placebo. While promising, human clinical trials remain limited.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Other
                
                
                n=80
                
                
                3 weeks
                
                
                Double-blind
                
            

            
                Investigation of the natural supplement IQP-AS-119 for the prevention of upper respiratory tract infections in …
            
            

                
                Dose: 20.0%
                
                
                vs: placebo
                
                
                Outcome: None
                
                
                效果: or 14
                
                
                P=0.038
                
            

            
            
研究人群: None

            
        

        
        

            

                
                    Other
                
                
                
                17.3 weeks
                
                
            

            
                Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Alzheimer's disease patients

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Treatment of the common cold in children and adults.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: infection rate
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Chemoprevention of bladder cancer.
            
            

                
                Dose: Various nutrients (selenium, vitamins, green tea)
                
                
                vs: None
                
                
                Outcome: Bladder cancer chemoprevention
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Bladder cancer patients

            
        

        
        

            

                
                    Meta-Analysis
                
                
                
                
            

            
                Unsafe and potentially safe herbal therapies.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: lipid levels
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: hypertensive patients

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
研究数量

    

    

        
300

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Investigation of the natural supplement IQP-AS-119 for the prevention of upper respiratory tract infections in marathon race participants: A randomized, …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Experimental and therapeutic …
                        2021
                        
                    

                

                
                

                    

                        
                            Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Neuromolecular medicine
                        2016
                        
                    

                

                
                

                    

                        
                            Treatment of the common cold in children and adults.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        American family physician
                        2012
                        
                    

                

                
                

                    

                        
                            Chemoprevention of bladder cancer.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        The Urologic clinics …
                        2002
                        
                        20 次引用
                        
                    

                

                
                

                    

                        
                            Unsafe and potentially safe herbal therapies.
                        
                        
                            
                                Meta-Analysis
                            
                            
                            
                        
                    

                    

                        American journal of …
                        1999
                        
                        226 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
fresh:

                        
2-5 g raw garlic/day

                    

                    
                    

                        
general:

                        
600-1,200 mg aged garlic extract/day

                    

                    
                

                
                

                    上限： No established UL; high doses may increase bleeding risk
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                20.0%
                                3 weeks
                                
                                    
                                    Mixed
                                    
                                
                                80
                            

                            
                            

                                None
                                17.3 weeks
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                Various nutrients (selenium, vitamins, green tea)
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： With meals to reduce GI discomfort
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort (heartburn, gas, nausea)
                        
    • 
                        
                        
  • 
                            ⚠
                            Body and breath odor
                        
    • 
                        
                        
  • 
                            ⚠
                            Increased bleeding risk
                        
    • 
                        
                        
  • 
                            ⚠
                            Allergic reactions (contact dermatitis, rare)
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants and antiplatelet drugs (may increase bleeding risk)
                        
    • 
                        
                        
  • 
                            ●
                            HIV protease inhibitors (saquinavir — may reduce drug levels)
                        
    • 
                        
                        
  • 
                            ●
                            CYP2E1 substrates (garlic may alter metabolism)
                        
    • 
                        
                        
  • 
                            ●
                            Isoniazid (may reduce drug absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： No established UL; high doses may increase bleeding risk
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Garlic help with Upper Respiratory Tract Infections?
            
        
        

            Based on 3 studies with 300 participants, there is moderate evidence from clinical studies that Garlic may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Garlic should I take for Upper Respiratory Tract Infections?
            
        
        

            Studies have used various dosages. A commonly studied range is 2-5 g raw garlic/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Garlic?
            
        
        

            Reported side effects may include Gastrointestinal discomfort (heartburn, gas, nausea), Body and breath odor, Increased bleeding risk, Allergic reactions (contact dermatitis, rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Garlic and Upper Respiratory Tract Infections?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

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