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ImmuneCited

Echinacea 用于 Upper Respiratory Tract Infections

B

Cochrane-reviewed meta-analyses suggest echinacea may modestly reduce cold duration and severity when started at symptom onset. Daily prophylactic use may reduce cold risk. Individual trial effects are small but consistently positive across multiple preparations.

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B

结论

Cochrane-reviewed meta-analyses suggest echinacea may modestly reduce cold duration and severity when started at symptom onset. Daily prophylactic use may reduce cold risk. Individual trial effects are small but consistently positive across multiple preparations.

Key Study Findings

Meta-Analysis n=3169
Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis …
Dose: None vs: Placebo Outcome: URTI treatment duration, incidence, antibiotic use 效果: SMD=-0.19 (duration); RR=0.81 (incidence) <0.01

研究人群: Children with URTI and otitis media (9 RCTs)

Review
Plant-Based Support of Respiratory Health during Viral Outbreaks.
Dose: None vs: None Outcome: None 效果: None None

研究人群: None

Meta-Analysis
Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and …
Dose: None vs: Placebo Outcome: Upper respiratory tract infection 效果: None None

研究人群: None

Meta-Analysis n=3135 13.0 weeks
Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A …
Dose: None vs: Placebo Outcome: Upper respiratory tract infection 效果: odds ratio = 0.75 p=0.07

研究人群: children

In Vitro
Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural …
Dose: None vs: Placebo Outcome: Influenza and common cold prevention/treatment 效果: None None

研究人群: General population with respiratory infections

Randomized Controlled Trial n=177 Double-blind
Antitussive effect of a fixed combination of Justicia adhatoda, Echinacea purpurea and Eleutherococcus senticosus extracts …
Dose: 30 ml/day vs: placebo Outcome: cough relief, which was assessed as the change … 效果: None None

研究人群: men

Key Statistics

20

研究数量

4000

受试者

Positive

B

等级

Referenced Papers

Journal of agricultural … 2022 9 次引用
American family physician 2012
International journal of … 2007 41 次引用
Southern medical journal 2005 35 次引用
Clinical evidence 2003
Clinical evidence 2003
American family physician 2002

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:
300-500 mg standardized extract 3x/day
acuteuse:
At first sign of symptoms for 7-10 days

上限: No established UL; generally used for 10 days or less

研究中使用的剂量

剂量 持续时间 效果 N
None -- Positive 3169
None -- Mixed --
None -- Positive --
None 13.0 weeks Mixed 3135
None -- Positive --
30 ml/day -- Positive 177
None -- Neutral --
None -- Mixed --

最佳服用时间: At first sign of symptoms; multiple doses throughout the day

Safety & Side Effects

已报告的副作用

  • Gastrointestinal upset (nausea, stomach pain)
  • Allergic reactions (especially in those allergic to daisies, ragweed)
  • Headache
  • Dizziness

已知相互作用

  • Immunosuppressant medications (may counteract immunosuppression)
  • CYP3A4 substrates (may alter metabolism of various drugs)
  • Caffeine (may slow caffeine metabolism)
  • Anabolic steroids and methotrexate (increased hepatotoxicity risk)

可耐受最高摄入量: No established UL; generally used for 10 days or less

在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Echinacea help with Upper Respiratory Tract Infections?
Based on 20 studies with 4,000 participants, there is moderate evidence from clinical studies that Echinacea may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).
How much Echinacea should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 300-500 mg standardized extract 3x/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Echinacea?
Reported side effects may include Gastrointestinal upset (nausea, stomach pain), Allergic reactions (especially in those allergic to daisies, ragweed), Headache, Dizziness. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Echinacea and Upper Respiratory Tract Infections?
We rate the evidence as Grade B (Good Evidence). This rating is based on 20 peer-reviewed studies with 4,000 total participants. The overall direction of effect is positive.

Related Evidence

FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。