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ImmuneCited

Echinacea per Upper Respiratory Tract Infections

B

Cochrane-reviewed meta-analyses suggest echinacea may modestly reduce cold duration and severity when started at symptom onset. Daily prophylactic use may reduce cold risk. Individual trial effects are small but consistently positive across multiple preparations.

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B

In sintesi

Cochrane-reviewed meta-analyses suggest echinacea may modestly reduce cold duration and severity when started at symptom onset. Daily prophylactic use may reduce cold risk. Individual trial effects are small but consistently positive across multiple preparations.

Key Study Findings

Meta-Analysis n=3169
Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis …
Dose: None vs: Placebo Outcome: URTI treatment duration, incidence, antibiotic use Effetto: SMD=-0.19 (duration); RR=0.81 (incidence) <0.01

Popolazione: Children with URTI and otitis media (9 RCTs)

Review
Plant-Based Support of Respiratory Health during Viral Outbreaks.
Dose: None vs: None Outcome: None Effetto: None None

Popolazione: None

Meta-Analysis
Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and …
Dose: None vs: Placebo Outcome: Upper respiratory tract infection Effetto: None None

Popolazione: None

Meta-Analysis n=3135 13.0 weeks
Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A …
Dose: None vs: Placebo Outcome: Upper respiratory tract infection Effetto: odds ratio = 0.75 p=0.07

Popolazione: children

In Vitro
Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural …
Dose: None vs: Placebo Outcome: Influenza and common cold prevention/treatment Effetto: None None

Popolazione: General population with respiratory infections

Randomized Controlled Trial n=177 Double-blind
Antitussive effect of a fixed combination of Justicia adhatoda, Echinacea purpurea and Eleutherococcus senticosus extracts …
Dose: 30 ml/day vs: placebo Outcome: cough relief, which was assessed as the change … Effetto: None None

Popolazione: men

Key Statistics

20

Studi

4000

Partecipanti

Positive

B

Grado

Referenced Papers

Journal of agricultural … 2022 9 citazioni
American family physician 2012
International journal of … 2007 41 citazioni
Southern medical journal 2005 35 citazioni
Clinical evidence 2003
Clinical evidence 2003
American family physician 2002

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

general:
300-500 mg standardized extract 3x/day
acuteuse:
At first sign of symptoms for 7-10 days

Limite massimo: No established UL; generally used for 10 days or less

Dosaggi studiati nella ricerca

Dosaggio Durata Effetto N
None -- Positive 3169
None -- Mixed --
None -- Positive --
None 13.0 weeks Mixed 3135
None -- Positive --
30 ml/day -- Positive 177
None -- Neutral --
None -- Mixed --

Momento migliore per l'assunzione: At first sign of symptoms; multiple doses throughout the day

Safety & Side Effects

Effetti collaterali segnalati

  • Gastrointestinal upset (nausea, stomach pain)
  • Allergic reactions (especially in those allergic to daisies, ragweed)
  • Headache
  • Dizziness

Interazioni note

  • Immunosuppressant medications (may counteract immunosuppression)
  • CYP3A4 substrates (may alter metabolism of various drugs)
  • Caffeine (may slow caffeine metabolism)
  • Anabolic steroids and methotrexate (increased hepatotoxicity risk)

Livello di assunzione massimo tollerabile: No established UL; generally used for 10 days or less

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Echinacea help with Upper Respiratory Tract Infections?
Based on 20 studies with 4,000 participants, there is moderate evidence from clinical studies that Echinacea may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).
How much Echinacea should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 300-500 mg standardized extract 3x/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Echinacea?
Reported side effects may include Gastrointestinal upset (nausea, stomach pain), Allergic reactions (especially in those allergic to daisies, ragweed), Headache, Dizziness. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Echinacea and Upper Respiratory Tract Infections?
We rate the evidence as Grade B (Good Evidence). This rating is based on 20 peer-reviewed studies with 4,000 total participants. The overall direction of effect is positive.

Related Evidence

Altri ingredienti per Upper Respiratory Tract Infections

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.