Spirulina 用于 Allergic Rhinitis

A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.

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结论

Key Study Findings

Controlled Clinical Trial 6 weeks

Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative …

Dose: 50 mg/kg/day vs: OVA-sensitized control without Spirulina Outcome: Tracheal reactivity to acetylcholine and citric acid 效果: None None

研究人群: OVA-sensitized Wistar rats

Other 12 weeks

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?

Dose: 92% vs: None Outcome: by ICPMS 效果: or 4 None

研究人群: None

Randomized Controlled Trial n=76 Open-label

Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK …

Dose: None vs: Control group Outcome: symptom control, assessed by the control of allergic … 效果: None p = 0.035

研究人群: Allergic rhinitis patients

In Vitro

Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 …

Dose: None vs: None Outcome: IgE-mediated TNF-alpha and histamine release 效果: None None

研究人群: RBL-2H3 mast cells

Review

Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology.

Dose: None vs: None Outcome: None 效果: None None

研究人群: Otorhinolaryngology patients (phytotherapy)

Review

Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis.

Dose: None vs: None Outcome: None 效果: None None

研究人群: allergic rhinitis patients

Key Statistics

研究数量

150

受试者

↑

Positive

等级

Referenced Papers

Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress. Other

Frontiers in pharmacology 2022 5 次引用

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? Other

Physiological reports 2021 3 次引用

Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes. Other

Clinical and translational … 2020 20 次引用

Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis. RCT

Acta otorhinolaryngologica Italica … 2020 11 次引用

Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in … Other

Plants (Basel, Switzerland) 2018 23 次引用

Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. Review

European annals of … 2017 16 次引用

Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis. Review

Recent patents on … 2015 16 次引用

Complementary therapies in allergic rhinitis. Other

ISRN allergy 2013 19 次引用

Complementary and alternative medicine for allergic rhinitis. Review

Current opinion in … 2009 26 次引用

The effects of spirulina on allergic rhinitis. RCT

European archives of … 2008 91 次引用

'Complementary ENT': a systematic review of commonly used supplements. Systematic Review

The Journal of … 2007 39 次引用

Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. RCT

Journal of medicinal … 2005 195 次引用

[Experimental study of spirulina platensis in treating allergic rhinitis in rats]. Other

Zhong nan da … 2005

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 1-3 g/day
immunesupport:: 3-10 g/day

上限： No established UL; 10 g/day widely studied

研究中使用的剂量

剂量	持续时间	效果	N
50 mg/kg/day	6 weeks	Positive	--
92%	12 weeks	Positive	--
None	--	Positive	76
None	--	Positive	--
None	--	Mixed	--
None	--	Positive	--
None	--	Neutral	230
None	--	Positive	--

最佳服用时间： With or without food

Safety & Side Effects

已报告的副作用

⚠ Gastrointestinal discomfort
⚠ Headache
⚠ Allergic reactions (rare)
⚠ Contamination risk from wild-harvested sources (microcystins, heavy metals)
⚠ May exacerbate autoimmune conditions (immunostimulatory)

已知相互作用

● Immunosuppressant medications (may counteract immunosuppression)
● Anticoagulants (may have additive effects)
● Diabetes medications (may lower blood sugar)

可耐受最高摄入量： No established UL; 10 g/day widely studied

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Spirulina help with Allergic Rhinitis?

Based on 3 studies with 150 participants, there is limited but promising evidence that Spirulina may support Allergic Rhinitis management. Our evidence grade is C (Some Evidence).

How much Spirulina should I take for Allergic Rhinitis?

Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Spirulina?

Reported side effects may include Gastrointestinal discomfort, Headache, Allergic reactions (rare), Contamination risk from wild-harvested sources (microcystins, heavy metals). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Spirulina and Allergic Rhinitis?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is positive.

Related Evidence

其他成分用于 Allergic Rhinitis

Quercetin C Astragalus C

快速结论

Evidence Strength52%

Moderate confidence

研究分析

RCT (3)Meta (0)Other (0)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于 Allergic Rhinitis

了解更多

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