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ImmuneCited

Elderberry لـ Influenza

B

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

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B

الخلاصة

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

Key Study Findings

Review
Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: review of Sambucus nigra biological activities and phytochemistry

In Vitro
Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza …
Dose: IC50 ~1:400 (EC 3.2), 250 nM (quinine) مقابل: Monotherapy and untreated controls Outcome: IAV and SARS-CoV-2 viral replication inhibition التأثير: Synergy scores 14.7 (IAV), 27.8 (SARS-CoV-2) None

المجتمع المدروس: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)

Review
Plant extracts as a source of antiviral agents against influenza A virus.
Dose: None مقابل: None Outcome: Antiviral effects against influenza A virus التأثير: None None

المجتمع المدروس: In vitro IAV models (review)

Other
Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: None

Review
Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications.
Dose: None مقابل: None Outcome: Antioxidant, anti-inflammatory, antiviral effects التأثير: None None

المجتمع المدروس: General population

Review
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Dose: None مقابل: None Outcome: Vascular function and antiviral properties التأثير: None None

المجتمع المدروس: COVID-19/cardiovascular populations

Key Statistics

5

الدراسات

500

المشاركون

Positive

B

التقييم

Referenced Papers

Journal of applied … 2025 3 اقتباسات
Journal of agricultural … 2022 71 اقتباسات
Journal of ethnopharmacology 2022 26 اقتباسات
Journal of agricultural … 2022 9 اقتباسات
BMC complementary medicine … 2021 57 اقتباسات
The Medical letter … 2019
Phytotherapy research : … 2017 98 اقتباسات
Phytotherapy research : … 2015 37 اقتباسات
Analytical and bioanalytical … 2013 51 اقتباسات
Bioscience, biotechnology, and … 2012 76 اقتباسات
Antiviral chemistry & … 2011 9 اقتباسات
Phytotherapy research : … 2010 102 اقتباسات
Phytochemistry 2009 234 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

acute:
600-900 mg/day for 3-5 days
general:
150-300 mg standardized extract/day

الحد الأعلى: No established UL; short-term use recommended

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
None -- Positive --
IC50 ~1:400 (EC 3.2), 250 nM (quinine) -- Positive --
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Mixed --

أفضل وقت للتناول: At first sign of symptoms; within 48 hours of onset for best results

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
  • Mild gastrointestinal effects with prepared extracts
  • Allergic reactions (rare)

التفاعلات المعروفة

  • Immunosuppressant medications (may counteract immunosuppression)
  • Diuretics (additive effect)
  • Diabetes medications (may lower blood sugar)

الحد الأقصى المسموح به: No established UL; short-term use recommended

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Elderberry help with Influenza?
Based on 5 studies with 500 participants, there is moderate evidence from clinical studies that Elderberry may support Influenza management. Our evidence grade is B (Good Evidence).
How much Elderberry should I take for Influenza?
Studies have used various dosages. A commonly studied range is 600-900 mg/day for 3-5 days. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elderberry?
Reported side effects may include Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides), Mild gastrointestinal effects with prepared extracts, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elderberry and Influenza?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.