Elderberry के लिए Influenza
B संबंधित साक्ष्य कम से कम एक यादृच्छिक परीक्षण इसका समर्थन करता है, जिसके परिणाम अधिकतर सुसंगत हैं।Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.
निष्कर्ष
Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.
Key Study Findings
जनसंख्या: review of Sambucus nigra biological activities and phytochemistry
जनसंख्या: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)
जनसंख्या: In vitro IAV models (review)
जनसंख्या: None
जनसंख्या: General population
जनसंख्या: COVID-19/cardiovascular populations
Key Statistics
5
अध्ययन
500
प्रतिभागी
Positive
ग्रेड
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- acute:
- 600-900 mg/day for 3-5 days
- general:
- 150-300 mg standardized extract/day
अधिकतम सीमा: No established UL; short-term use recommended
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | -- | Positive | -- |
| IC50 ~1:400 (EC 3.2), 250 nM (quinine) | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
सेवन का सर्वोत्तम समय: At first sign of symptoms; within 48 hours of onset for best results
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
- ⚠ Mild gastrointestinal effects with prepared extracts
- ⚠ Allergic reactions (rare)
ज्ञात अंतःक्रियाएँ
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Diuretics (additive effect)
- ● Diabetes medications (may lower blood sugar)
सहनीय अधिकतम सेवन: No established UL; short-term use recommended
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Elderberry help with Influenza?
How much Elderberry should I take for Influenza?
Are there side effects of Elderberry?
How strong is the evidence for Elderberry and Influenza?
References
- [1] Asmaa M Khalil et al.. Inflammopharmacology. 2026. Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant. doi:10.1007/s10787-025-02017-0 PubMed
- [2] Christian Setz et al.. Nutrients. 2025. Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza A Virusa. doi:10.3390/nu17071205 PubMed
- [3] Hanushree Arumugam et al.. J Appl Microbiol. 2025. Plant extracts as a source of antiviral agents against influenza A virus. doi:10.1093/jambio/lxaf056 PubMed
- [4] Dan Liu et al.. J Agric Food Chem. 2022. Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications. doi:10.1021/acs.jafc.2c00010 PubMed
- [5] José Roberto Santin et al.. J Ethnopharmacol. 2022. Sambucus nigra: A traditional medicine effective in reducing inflammation in mice. doi:10.1016/j.jep.2021.114736 PubMed
- [6] Maren Eggers et al.. Phytother Res. 2022. Antiviral activity of plant juices and green tea against SARS-CoV-2 and influenza virus. doi:10.1002/ptr.7431 PubMed
- [7] Michał Ochnik et al.. Pharmaceuticals (Basel). 2022. Inhibition of Human Respiratory Influenza A Virus and Human Betacoronavirus-1 by the Blend of Double-Standardized Extracts of Aronia melanocarpa (Michx.) … doi:10.3390/ph15050619 PubMed
- [8] Joseph Festa et al.. J Food Biochem. 2022. Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment. doi:10.1111/jfbc.14091 PubMed
- [9] Lena Stich et al.. Int J Mol Sci. 2022. Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses. doi:10.3390/ijms23073949 PubMed
- [10] Thirumurugan Rathinasabapathy et al.. J Agric Food Chem. 2022. Plant-Based Support of Respiratory Health during Viral Outbreaks. doi:10.1021/acs.jafc.1c06227 PubMed
- [11] L Susan Wieland et al.. BMC Complement Med Ther. 2021. Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review. doi:10.1186/s12906-021-03283-5 PubMed
- [12] Preksha Shahagadkar et al.. Clin Nutr ESPEN. 2021. Berry derived constituents in suppressing viral infection: Potential avenues for viral pandemic management. doi:10.1016/j.clnesp.2021.09.728 PubMed
- [13] Michael Macknin et al.. J Gen Intern Med. 2020. Elderberry Extract Outpatient Influenza Treatment for Emergency Room Patients Ages 5 and Above: a Randomized, Double-Blind, Placebo-Controlled Trial. doi:10.1007/s11606-020-06170-w PubMed
- [14] Jessie Hawkins et al.. Complement Ther Med. 2019. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. doi:10.1016/j.ctim.2018.12.004 PubMed
- [15] . Med Lett Drugs Ther. 2019. Elderberry for influenza. PubMed
- [16] Claudio Andrés Álvarez et al.. Molecules. 2018. Identification of Peptides in Flowers of Sambucus nigra with Antimicrobial Activity against Aquaculture Pathogens. doi:10.3390/molecules23051033 PubMed
- [17] Randall S Porter et al.. Phytother Res. 2017. A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. doi:10.1002/ptr.5782 PubMed
- [18] Evelin Tiralongo et al.. Nutrients. 2016. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. doi:10.3390/nu8040182 PubMed
- [19] Christian Vlachojannis et al.. Phytother Res. 2015. Quantification of anthocyanins in elderberry and chokeberry dietary supplements. doi:10.1002/ptr.5284 PubMed
- [20] Lone Holst et al.. Front Pharmacol. 2014. Echinacea and elderberry-should they be used against upper respiratory tract infections during pregnancy? doi:10.3389/fphar.2014.00031 PubMed
- [21] Kavya Swaminathan et al.. Anal Bioanal Chem. 2013. Binding of a natural anthocyanin inhibitor to influenza neuraminidase by mass spectrometry. doi:10.1007/s00216-013-7068-x PubMed
- [22] Emiko Kinoshita et al.. Biosci Biotechnol Biochem. 2012. Anti-influenza virus effects of elderberry juice and its fractions. doi:10.1271/bbb.120112 PubMed
- [23] Stella Zevgiti et al.. J Pept Sci. 2012. Sialic acid and sialyl-lactose glyco-conjugates: design, synthesis and binding assays to lectins and swine influenza H1N1 virus. doi:10.1002/psc.1415 PubMed
- [24] Christian Krawitz et al.. BMC Complement Altern Med. 2011. Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses. doi:10.1186/1472-6882-11-16 PubMed
- [25] Donald F Smee et al.. Antivir Chem Chemother. 2011. Effects of TheraMax on influenza virus infections in cell culture and in mice. doi:10.3851/IMP1744 PubMed
- [26] J E Vlachojannis et al.. Phytother Res. 2010. A systematic review on the sambuci fructus effect and efficacy profiles. doi:10.1002/ptr.2729 PubMed
- [27] Bill Roschek et al.. Phytochemistry. 2009. Elderberry flavonoids bind to and prevent H1N1 infection in vitro. doi:10.1016/j.phytochem.2009.06.003 PubMed
- [28] Mario Roxas et al.. Altern Med Rev. 2007. Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations. PubMed
- [29] Z Zakay-Rones et al.. J Int Med Res. 2004. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus … doi:10.1177/147323000403200205 PubMed
- [30] Vivian Barak et al.. Isr Med Assoc J. 2002. The effect of herbal remedies on the production of human inflammatory and anti-inflammatory cytokines. PubMed
- [31] V Barak et al.. Eur Cytokine Netw. 2001. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. PubMed
- [32] Z Zakay-Rones et al.. J Altern Complement Med. 1995. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) … doi:10.1089/acm.1995.1.361 PubMed
FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।