Elderberry para Influenza
B Evidencia Al menos un ensayo aleatorizado lo respalda, con resultados mayoritariamente consistentes.Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.
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B
Conclusión
Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.
Key Study Findings
Review
Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant.
Dose: None
vs: None
Outcome: None
Efecto: None
None
Población: review of Sambucus nigra biological activities and phytochemistry
In Vitro
Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza …
Dose: IC50 ~1:400 (EC 3.2), 250 nM (quinine)
vs: Monotherapy and untreated controls
Outcome: IAV and SARS-CoV-2 viral replication inhibition
Efecto: Synergy scores 14.7 (IAV), 27.8 (SARS-CoV-2)
None
Población: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)
Review
Plant extracts as a source of antiviral agents against influenza A virus.
Dose: None
vs: None
Outcome: Antiviral effects against influenza A virus
Efecto: None
None
Población: In vitro IAV models (review)
Other
Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses.
Dose: None
vs: None
Outcome: None
Efecto: None
None
Población: None
Review
Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications.
Dose: None
vs: None
Outcome: Antioxidant, anti-inflammatory, antiviral effects
Efecto: None
None
Población: General population
Review
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Dose: None
vs: None
Outcome: Vascular function and antiviral properties
Efecto: None
None
Población: COVID-19/cardiovascular populations
Key Statistics
5
Estudios
500
Participantes
↑
Positive
B
Calificación
Referenced Papers
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2026
Nutrients
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5 citas
Journal of applied …
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Journal of agricultural …
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71 citas
Journal of ethnopharmacology
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Phytotherapy research : …
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Pharmaceuticals (Basel, Switzerland)
2022
14 citas
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Review
Journal of food …
2022
13 citas
International journal of …
2022
12 citas
Journal of agricultural …
2022
9 citas
Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review.
Systematic Review
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2021
57 citas
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2021
5 citas
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2020
14 citas
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109 citas
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29 citas
Phytotherapy research : …
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98 citas
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98 citas
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2015
37 citas
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14 citas
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2013
51 citas
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2012
76 citas
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25 citas
BMC complementary and …
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159 citas
Antiviral chemistry & …
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9 citas
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Systematic Review
Phytotherapy research : …
2010
102 citas
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2009
234 citas
Alternative medicine review …
2007
163 citas
The Journal of …
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Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosificaciones de uso común
- acute:
- 600-900 mg/day for 3-5 days
- general:
- 150-300 mg standardized extract/day
Límite superior: No established UL; short-term use recommended
Dosificaciones estudiadas en la investigación
| Dosificación | Duración | Efecto | N |
|---|---|---|---|
| None | -- | Positive | -- |
| IC50 ~1:400 (EC 3.2), 250 nM (quinine) | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
Mejor momento para tomar: At first sign of symptoms; within 48 hours of onset for best results
Safety & Side Effects
Efectos secundarios reportados
- ⚠ Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
- ⚠ Mild gastrointestinal effects with prepared extracts
- ⚠ Allergic reactions (rare)
Interacciones conocidas
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Diuretics (additive effect)
- ● Diabetes medications (may lower blood sugar)
Ingesta máxima tolerable: No established UL; short-term use recommended
Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.
Frequently Asked Questions
Does Elderberry help with Influenza?
Based on 5 studies with 500 participants, there is moderate evidence from clinical studies that Elderberry may support Influenza management. Our evidence grade is B (Good Evidence).
How much Elderberry should I take for Influenza?
Studies have used various dosages. A commonly studied range is 600-900 mg/day for 3-5 days. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elderberry?
Reported side effects may include Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides), Mild gastrointestinal effects with prepared extracts, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elderberry and Influenza?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.
References
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Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.