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Elderberry для Influenza

B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

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Итог

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

Key Study Findings

Review
Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant.
Dose: None или: None Outcome: None Эффект: None None

Популяция: review of Sambucus nigra biological activities and phytochemistry

In Vitro
Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza …
Dose: IC50 ~1:400 (EC 3.2), 250 nM (quinine) или: Monotherapy and untreated controls Outcome: IAV and SARS-CoV-2 viral replication inhibition Эффект: Synergy scores 14.7 (IAV), 27.8 (SARS-CoV-2) None

Популяция: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)

Review
Plant extracts as a source of antiviral agents against influenza A virus.
Dose: None или: None Outcome: Antiviral effects against influenza A virus Эффект: None None

Популяция: In vitro IAV models (review)

Other
Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses.
Dose: None или: None Outcome: None Эффект: None None

Популяция: None

Review
Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications.
Dose: None или: None Outcome: Antioxidant, anti-inflammatory, antiviral effects Эффект: None None

Популяция: General population

Review
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Dose: None или: None Outcome: Vascular function and antiviral properties Эффект: None None

Популяция: COVID-19/cardiovascular populations

Key Statistics

5

Исследования

500

Участники

Positive

B

Оценка

Referenced Papers

Journal of applied … 2025 3 цитирований
Journal of agricultural … 2022 71 цитирований
Journal of ethnopharmacology 2022 26 цитирований
Phytotherapy research : … 2022 15 цитирований
Journal of agricultural … 2022 9 цитирований
BMC complementary medicine … 2021 57 цитирований
The Medical letter … 2019
Phytotherapy research : … 2017 98 цитирований
Phytotherapy research : … 2015 37 цитирований
Analytical and bioanalytical … 2013 51 цитирований
Bioscience, biotechnology, and … 2012 76 цитирований
Antiviral chemistry & … 2011 9 цитирований
Phytotherapy research : … 2010 102 цитирований
Phytochemistry 2009 234 цитирований
Alternative medicine review … 2007 163 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

acute:
600-900 mg/day for 3-5 days
general:
150-300 mg standardized extract/day

Верхний предел: No established UL; short-term use recommended

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Positive --
IC50 ~1:400 (EC 3.2), 250 nM (quinine) -- Positive --
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Mixed --

Лучшее время приёма: At first sign of symptoms; within 48 hours of onset for best results

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
  • Mild gastrointestinal effects with prepared extracts
  • Allergic reactions (rare)

Известные взаимодействия

  • Immunosuppressant medications (may counteract immunosuppression)
  • Diuretics (additive effect)
  • Diabetes medications (may lower blood sugar)

Допустимый верхний уровень потребления: No established UL; short-term use recommended

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Elderberry help with Influenza?
Based on 5 studies with 500 participants, there is moderate evidence from clinical studies that Elderberry may support Influenza management. Our evidence grade is B (Good Evidence).
How much Elderberry should I take for Influenza?
Studies have used various dosages. A commonly studied range is 600-900 mg/day for 3-5 days. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elderberry?
Reported side effects may include Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides), Mild gastrointestinal effects with prepared extracts, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elderberry and Influenza?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

References

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  4. [4] Dan Liu et al.. J Agric Food Chem. 2022. Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications. doi:10.1021/acs.jafc.2c00010 PubMed
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