Spirulina for Allergic Rhinitis
CA 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.
The Bottom Line
A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.
Key Study Findings
Population: OVA-sensitized Wistar rats
Population: None
Population: Allergic rhinitis patients
Population: RBL-2H3 mast cells
Population: Otorhinolaryngology patients (phytotherapy)
Population: allergic rhinitis patients
Key Statistics
3
Studies
150
Participants
Positive
Grade
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Commonly Used Dosages
- general:
- 1-3 g/day
- immunesupport:
- 3-10 g/day
Upper limit: No established UL; 10 g/day widely studied
Dosages Studied in Research
| Dosage | Duration | Effect | N |
|---|---|---|---|
| 50 mg/kg/day | 6 weeks | Positive | -- |
| 92% | 12 weeks | Positive | -- |
| None | -- | Positive | 76 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | 230 |
| None | -- | Positive | -- |
Best taken: With or without food
Safety & Side Effects
Reported Side Effects
- ⚠ Gastrointestinal discomfort
- ⚠ Headache
- ⚠ Allergic reactions (rare)
- ⚠ Contamination risk from wild-harvested sources (microcystins, heavy metals)
- ⚠ May exacerbate autoimmune conditions (immunostimulatory)
Known Interactions
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Anticoagulants (may have additive effects)
- ● Diabetes medications (may lower blood sugar)
Tolerable upper intake: No established UL; 10 g/day widely studied
Always consult your healthcare provider before starting any supplement.
Frequently Asked Questions
Does Spirulina help with Allergic Rhinitis?
How much Spirulina should I take for Allergic Rhinitis?
Are there side effects of Spirulina?
How strong is the evidence for Spirulina and Allergic Rhinitis?
Related Evidence
Other ingredients for Allergic Rhinitis
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.