Resveratrol untuk Chronic Inflammation
CPreclinical models demonstrate immunomodulatory and anti-inflammatory effects through SIRT1 and NF-kB modulation. Human trials show reduction in CRP and other inflammatory markers, though low oral bioavailability remains a key limitation.
Kesimpulan
Preclinical models demonstrate immunomodulatory and anti-inflammatory effects through SIRT1 and NF-kB modulation. Human trials show reduction in CRP and other inflammatory markers, though low oral bioavailability remains a key limitation.
Key Study Findings
Populasi: review of nutrition and lifestyle interventions for dyslipidemia and cardiometabolic risk
Populasi: None
Populasi: None
Populasi: review of NF-kB and M1 macrophages in asthma, COPD, and pulmonary fibrosis
Populasi: None
Populasi: review of plant-derived anti-inflammatory compounds for chronic disease prevention
Key Statistics
5
Studi
300
Peserta
Positive
Peringkat
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 150-500 mg/day
- immunesupport:
- 250-500 mg/day trans-resveratrol
Batas atas: No established UL; generally well-tolerated up to 1,500 mg/day
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
Waktu terbaik diminum: With meals
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Gastrointestinal discomfort (nausea, diarrhea)
- ⚠ Headache
- ⚠ Joint pain at very high doses (>2.5 g/day)
- ⚠ Kidney issues at extremely high doses (case reports)
Interaksi yang Diketahui
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- ● CYP1A2, CYP3A4 substrates (may inhibit metabolism)
- ● Estrogen-sensitive conditions (weak estrogenic activity)
Asupan atas yang dapat ditoleransi: No established UL; generally well-tolerated up to 1,500 mg/day
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Resveratrol help with Chronic Inflammation?
How much Resveratrol should I take for Chronic Inflammation?
Are there side effects of Resveratrol?
How strong is the evidence for Resveratrol and Chronic Inflammation?
Related Evidence
Bahan lain untuk Chronic Inflammation
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