Resveratrol 관련 Chronic Inflammation
CPreclinical models demonstrate immunomodulatory and anti-inflammatory effects through SIRT1 and NF-kB modulation. Human trials show reduction in CRP and other inflammatory markers, though low oral bioavailability remains a key limitation.
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C
결론
Preclinical models demonstrate immunomodulatory and anti-inflammatory effects through SIRT1 and NF-kB modulation. Human trials show reduction in CRP and other inflammatory markers, though low oral bioavailability remains a key limitation.
Key Study Findings
Review
Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
Review
Modulating Ferroptosis in Aging: The Therapeutic Potential of Natural Products.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
Review
Mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease: Effects of Polyphenols and Omega-3 Polyunsaturated Fatty …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
Review
Lysosomal Stress in Cardiovascular Diseases: Therapeutic Potential of Cardiovascular Drugs and Future Directions.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
In Vitro
Resveratrol derivative SH-707 inhibits NLRP3 inflammasome activation via a sirtuin 1-dependent pathway.
Dose: None
vs: LPS-induced septic mouse model vs control
Outcome: IL-1β secretion and NLRP3 inflammasome activation
효과: None
None
대상 집단: Macrophages and LPS-induced septic mouse model
Other
Gut microbiota-metabolite crosstalk mediates icariin's protection against obesity-induced spermatogenic dysfunction through NF-κB/AMH axis in Sertoli …
Dose: None
vs: HFD mouse model vs control
Outcome: Testicular morphology and spermatogenesis markers
효과: None
None
대상 집단: HFD-induced obese mouse model (spermatogenesis)
Key Statistics
5
연구
300
참여자
↑
Positive
C
등급
Referenced Papers
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2025
58 인용
Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus.
Review
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Systematic Review
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Antitumor Effects of Resveratrol Opposing Mechanisms of Helicobacter pylori in Gastric Cancer.
Review
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Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease.
Review
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2020
144 인용
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2020
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Review
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2018
107 인용
MiR-663, a MicroRNA Linked with Inflammation and Cancer That Is under the Influence of Resveratrol.
Review
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2018
23 인용
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2018
13 인용
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2017
63 인용
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2017
48 인용
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2015
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2015
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2013
73 인용
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Review
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2011
97 인용
Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin.
Review
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2008
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2006
92 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 150-500 mg/day
- immunesupport:
- 250-500 mg/day trans-resveratrol
상한량: No established UL; generally well-tolerated up to 1,500 mg/day
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
권장 복용 시간: With meals
Safety & Side Effects
보고된 부작용
- ⚠ Gastrointestinal discomfort (nausea, diarrhea)
- ⚠ Headache
- ⚠ Joint pain at very high doses (>2.5 g/day)
- ⚠ Kidney issues at extremely high doses (case reports)
알려진 상호작용
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- ● CYP1A2, CYP3A4 substrates (may inhibit metabolism)
- ● Estrogen-sensitive conditions (weak estrogenic activity)
일일 최대 섭취 허용량: No established UL; generally well-tolerated up to 1,500 mg/day
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Resveratrol help with Chronic Inflammation?
Based on 5 studies with 300 participants, there is limited but promising evidence that Resveratrol may support Chronic Inflammation management. Our evidence grade is C (Some Evidence).
How much Resveratrol should I take for Chronic Inflammation?
Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea), Headache, Joint pain at very high doses (>2.5 g/day), Kidney issues at extremely high doses (case reports). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and Chronic Inflammation?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: Chronic Inflammation
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.