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ImmuneCited

Elderberry per Influenza

B

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

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In sintesi

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

Key Study Findings

Review
Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant.
Dose: None vs: None Outcome: None Effetto: None None

Popolazione: review of Sambucus nigra biological activities and phytochemistry

In Vitro
Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza …
Dose: IC50 ~1:400 (EC 3.2), 250 nM (quinine) vs: Monotherapy and untreated controls Outcome: IAV and SARS-CoV-2 viral replication inhibition Effetto: Synergy scores 14.7 (IAV), 27.8 (SARS-CoV-2) None

Popolazione: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)

Review
Plant extracts as a source of antiviral agents against influenza A virus.
Dose: None vs: None Outcome: Antiviral effects against influenza A virus Effetto: None None

Popolazione: In vitro IAV models (review)

Other
Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses.
Dose: None vs: None Outcome: None Effetto: None None

Popolazione: None

Review
Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications.
Dose: None vs: None Outcome: Antioxidant, anti-inflammatory, antiviral effects Effetto: None None

Popolazione: General population

Review
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Dose: None vs: None Outcome: Vascular function and antiviral properties Effetto: None None

Popolazione: COVID-19/cardiovascular populations

Key Statistics

5

Studi

500

Partecipanti

Positive

B

Grado

Referenced Papers

Journal of agricultural … 2022 9 citazioni
BMC complementary medicine … 2021 57 citazioni
The Medical letter … 2019
Bioscience, biotechnology, and … 2012 76 citazioni
Phytotherapy research : … 2010 102 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

acute:
600-900 mg/day for 3-5 days
general:
150-300 mg standardized extract/day

Limite massimo: No established UL; short-term use recommended

Dosaggi studiati nella ricerca

Dosaggio Durata Effetto N
None -- Positive --
IC50 ~1:400 (EC 3.2), 250 nM (quinine) -- Positive --
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Mixed --

Momento migliore per l'assunzione: At first sign of symptoms; within 48 hours of onset for best results

Safety & Side Effects

Effetti collaterali segnalati

  • Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
  • Mild gastrointestinal effects with prepared extracts
  • Allergic reactions (rare)

Interazioni note

  • Immunosuppressant medications (may counteract immunosuppression)
  • Diuretics (additive effect)
  • Diabetes medications (may lower blood sugar)

Livello di assunzione massimo tollerabile: No established UL; short-term use recommended

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Elderberry help with Influenza?
Based on 5 studies with 500 participants, there is moderate evidence from clinical studies that Elderberry may support Influenza management. Our evidence grade is B (Good Evidence).
How much Elderberry should I take for Influenza?
Studies have used various dosages. A commonly studied range is 600-900 mg/day for 3-5 days. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elderberry?
Reported side effects may include Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides), Mild gastrointestinal effects with prepared extracts, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elderberry and Influenza?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.