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ImmuneCited

Elderberry para Influenza

B

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

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B

Conclusão

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

Key Study Findings

Review
Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant.
Dose: None vs: None Outcome: None Efeito: None None

População: review of Sambucus nigra biological activities and phytochemistry

In Vitro
Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza …
Dose: IC50 ~1:400 (EC 3.2), 250 nM (quinine) vs: Monotherapy and untreated controls Outcome: IAV and SARS-CoV-2 viral replication inhibition Efeito: Synergy scores 14.7 (IAV), 27.8 (SARS-CoV-2) None

População: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)

Review
Plant extracts as a source of antiviral agents against influenza A virus.
Dose: None vs: None Outcome: Antiviral effects against influenza A virus Efeito: None None

População: In vitro IAV models (review)

Other
Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses.
Dose: None vs: None Outcome: None Efeito: None None

População: None

Review
Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications.
Dose: None vs: None Outcome: Antioxidant, anti-inflammatory, antiviral effects Efeito: None None

População: General population

Review
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Dose: None vs: None Outcome: Vascular function and antiviral properties Efeito: None None

População: COVID-19/cardiovascular populations

Key Statistics

5

Estudos

500

Participantes

Positive

B

Nota

Referenced Papers

Journal of agricultural … 2022 9 citações
BMC complementary medicine … 2021 57 citações
The Medical letter … 2019
Bioscience, biotechnology, and … 2012 76 citações
Phytotherapy research : … 2010 102 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

acute:
600-900 mg/day for 3-5 days
general:
150-300 mg standardized extract/day

Limite superior: No established UL; short-term use recommended

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
None -- Positive --
IC50 ~1:400 (EC 3.2), 250 nM (quinine) -- Positive --
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Mixed --

Melhor horário: At first sign of symptoms; within 48 hours of onset for best results

Safety & Side Effects

Efeitos Colaterais Relatados

  • Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
  • Mild gastrointestinal effects with prepared extracts
  • Allergic reactions (rare)

Interações Conhecidas

  • Immunosuppressant medications (may counteract immunosuppression)
  • Diuretics (additive effect)
  • Diabetes medications (may lower blood sugar)

Ingestão máxima tolerável: No established UL; short-term use recommended

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Elderberry help with Influenza?
Based on 5 studies with 500 participants, there is moderate evidence from clinical studies that Elderberry may support Influenza management. Our evidence grade is B (Good Evidence).
How much Elderberry should I take for Influenza?
Studies have used various dosages. A commonly studied range is 600-900 mg/day for 3-5 days. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elderberry?
Reported side effects may include Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides), Mild gastrointestinal effects with prepared extracts, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elderberry and Influenza?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.