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ImmuneCited

Elderberry für Influenza

B

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

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B

Fazit

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

Key Study Findings

Review
Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant.
Dose: None vs.: None Outcome: None Wirkung: None None

Population: review of Sambucus nigra biological activities and phytochemistry

In Vitro
Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza …
Dose: IC50 ~1:400 (EC 3.2), 250 nM (quinine) vs.: Monotherapy and untreated controls Outcome: IAV and SARS-CoV-2 viral replication inhibition Wirkung: Synergy scores 14.7 (IAV), 27.8 (SARS-CoV-2) None

Population: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)

Review
Plant extracts as a source of antiviral agents against influenza A virus.
Dose: None vs.: None Outcome: Antiviral effects against influenza A virus Wirkung: None None

Population: In vitro IAV models (review)

Other
Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses.
Dose: None vs.: None Outcome: None Wirkung: None None

Population: None

Review
Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications.
Dose: None vs.: None Outcome: Antioxidant, anti-inflammatory, antiviral effects Wirkung: None None

Population: General population

Review
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Dose: None vs.: None Outcome: Vascular function and antiviral properties Wirkung: None None

Population: COVID-19/cardiovascular populations

Key Statistics

5

Studien

500

Teilnehmer

Positive

B

Bewertung

Referenced Papers

Journal of agricultural … 2022 9 Zitierungen
BMC complementary medicine … 2021 57 Zitierungen
The Medical letter … 2019
Bioscience, biotechnology, and … 2012 76 Zitierungen
Phytotherapy research : … 2010 102 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

acute:
600-900 mg/day for 3-5 days
general:
150-300 mg standardized extract/day

Obergrenze: No established UL; short-term use recommended

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None -- Positive --
IC50 ~1:400 (EC 3.2), 250 nM (quinine) -- Positive --
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Mixed --

Beste Einnahmezeit: At first sign of symptoms; within 48 hours of onset for best results

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
  • Mild gastrointestinal effects with prepared extracts
  • Allergic reactions (rare)

Bekannte Wechselwirkungen

  • Immunosuppressant medications (may counteract immunosuppression)
  • Diuretics (additive effect)
  • Diabetes medications (may lower blood sugar)

Tolerierbare Höchstaufnahmemenge: No established UL; short-term use recommended

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Elderberry help with Influenza?
Based on 5 studies with 500 participants, there is moderate evidence from clinical studies that Elderberry may support Influenza management. Our evidence grade is B (Good Evidence).
How much Elderberry should I take for Influenza?
Studies have used various dosages. A commonly studied range is 600-900 mg/day for 3-5 days. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elderberry?
Reported side effects may include Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides), Mild gastrointestinal effects with prepared extracts, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elderberry and Influenza?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

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